A fully automated analytical platform integrating water sampling-miniscale-liquid-liquid extraction-full evaporation dynamic headspace concentration-gas chromatography-mass spectrometry for the analysis of ultraviolet filters

Water Analysis: Emerging Contaminants and Current Issues

“…Liew reported a fully automated sampling-sample preparationanalysis platform using a modified vial, peristaltic pump, mini-scale liquid−liquid extraction, evaporation, and GC−MS to measure six UV filters. 200 LODs ranged from 0.6 to 9.7 ng/ L, recoveries ranged from 62 to 80.7%, and good linearity was observed for benzhydrol, 2-ethylhexyl salicylate, homosalate, 2hydroxy-methoxybenzophenone, 3-(4′-methylbenzylidene)camphor, and benzophenone. This new method was subsequently demonstrated on swimming pool water, where recoveries ranged from 85.4 to 118.2%, and it was recommended for onsite water analysis.…”

“…Finally, there were some new methods reported for the measurement of UV filters in environmental waters. Liew reported a fully automated sampling-sample preparation-analysis platform using a modified vial, peristaltic pump, mini-scale liquid–liquid extraction, evaporation, and GC–MS to measure six UV filters . LODs ranged from 0.6 to 9.7 ng/L, recoveries ranged from 62 to 80.7%, and good linearity was observed for benzhydrol, 2-ethylhexyl salicylate, homosalate, 2-hydroxy-methoxybenzophenone, 3-(4′-methylbenzylidene)­camphor, and benzophenone.…”

Recent Progress in Fast Sample Preparation Techniques

“…A mini scale LLE method was developed by Lee's group and used for water quality monitoring by coupling with a headspace concentration and gas chromatography/mass spectrometry (GC/MS). 99 This method allowed 15 mL sample prepared in 80 min. Although the time saving effect is limited when compared with normal LLE, it is still a theoretically feasible way to cut down the duration of sample preparation.…”

“…A mini scale LLE method was developed by Lee’s group and used for water quality monitoring by coupling with a headspace concentration and gas chromatography/mass spectrometry (GC/MS) . This method allowed 15 mL sample prepared in 80 min.…”

Simultaneous estimation of dimenhydrinate, cinnarizine and their toxic impurities benzophenone and diphenylmethylpiperazine; in silico toxicity profiling of impurities

“…9 Reviewing the reported toxicity studies of BZP and BZH revealed higher and wider toxic effects for BZP. [10][11][12][13] Cinnarizine (CIN), 1-(diphenylmethyl)-4-(3-phenyl-2propenyl)piperazine (Fig. 1d) is a piperazine derivative with antihistaminic and calcium channel blocking activities.…”