30-Day Morbidity and Bleeding Rates Associated with Transoral Robotic Surgery for HPV Associated Oropharyngeal Squamous Cell Carcinoma: A Retrospective Analysis of Two Prospective Adjuvant Radiotherapy Deescalation Trials (MC1273 &amp; MC1675)

Haller, T.J.; O’Byrne, Thomas J.; Moore, Eric J.; Ma, Daniel; Price, Katharine A.; Patel, S.H.; Hinni, M.L.; Neben-Wittich, M.A.; McGee, L.A.; Price, D.L.; Janus, J.R.; Kasperbauer, Jan L.; Nagel, Thomas H.; Chintakuntlawar, Ashish V.; Savvides, P.; García, Joaquín J.; Foote, Robert L.; Abel, K. Van

doi:10.1016/j.ijrobp.2021.12.127

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“…11,12 A need to understand surgical disparities is especially poignant for oropharyngeal squamous cell carcinoma, a disease for which innumerable de-escalation protocols centered on transoral surgical techniques and novel adjuvant therapy protocols have been proposed and conducted over the last decade. [13][14][15][16][17] There is also evidence now of a rising diversity in the HPV(+)OPSCC cancer patient population, 18 an age range extending above 65, 19 and a wide range of smoking histories. 20 In addition, there has been a documented failure to appropriately test for HPV in minority communities, potentially underestimating the impact HPV has had on these communities.…”

Section: Introductionmentioning

confidence: 99%

Racial disparities in surgical treatment of oropharyngeal cancer: A Surveillance, Epidemiology, and End Results review

et al. 2023

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ObjectivesOropharyngeal squamous cell carcinoma (OPSCC) has been rising. This manuscript looks to explore racial disparities in the surgical management of OPSCC.MethodsA cancer database was queried for patients with OPSCC diagnosed from 2004 to 2017. Univariate and multivariable logistic regressions were used to evaluate associations between patient race/ethnicity, surgical treatment, and reasons for lack of surgery.Results37 306 (74.3%) patients did not undergo surgery, while 12 901 (25.7%) patients did. Non‐Hispanic black (NHB) patients were less likely to undergo surgery than other races (17.9% vs. 26.5%; p < 0.0001). In clinical discussions, the Asian, Native American, Hawaiian, Pacific Islander (ANAHPI), and unknown race group was more likely to directly refuse surgery when recommended (2.5% vs. 1.5%; p = 0.015).ConclusionRacial differences exist in treatment for OPSCC. NHB patients are less likely to actually undergo surgical management for OPSCC, while other patients are more likely to directly “refuse” surgery outright when offered.

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