3.P.206 Activation of human endothelial cells by minimally modified LDL and lysophosphatidylcholine: Investigation of the underlying signalling cascades

Geron, Ifat; Holvoet, Paul; Kinard, Fabienne; Remacle, Jean-François; Raes, Martine

doi:10.1016/s0021-9150(97)89280-5

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2007

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“…Atherosclerosis is the main cause of coronary heart disease, brain stroke and limb necrosis [1] and it is a complex disease, encompassing both a chronic process characterized by vascular inflammatory reactions, and having acute features, such as plaque rupture and endothelial injury [2][3][4]. Drugs applied to antiatherosclerotic therapies have different acting mechanisms because of the different pathological processes of atherosclerosis [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%