“…This was even more pronounced in those patients who could be rendered disease-free by surgical excision (Hsueh et al, 1998a;1998b;Morton et al, 1992). Our own group has recently confirmed this trend in a smaller phase II study which has now been closed, with the introduction of the double-blind randomized placebo control studies for stage III and stage IV patients with metastatic melanoma (Maraveyas et al, 1999b).…”