3-D conformal treatment of prostate cancer to 74 Gy vs. high-dose-rate brachytherapy boost: A cross-sectional quality-of-life survey

Vordermark, Dirk; Wulf, Jörn; Markert, Klaus; Baier, Kurt; Kölbl, Oliver; Beckmann, Gabriele; Bratengeier, Klaus; Noë, Michaël; Schön, Georg; Flentje, Michael

doi:10.1080/02841860600710913

Cited by 22 publications

(8 citation statements)

References 25 publications

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“…Furthermore, among patients with advanced cancer, a diagnosis of prostate, breast, lung, and gastrointestinal cancer was associated with increased likelihood of insomnia [28] . Insomnia among prostate cancer patients was also reportedly higher than in the general population [19] .…”

Section: Insomnia and Different Cancer Sitesmentioning

confidence: 99%

“…In studies investigating the HRQoL of men with prostate cancer, insomnia is consistently the symptom that receives the highest score [19] or one of the highest scores, indicating worse symptomology [8,12,14,15,23,26] . Higher symptomology is associated with lower HRQoL among men with prostate cancer into survivorship [14] .…”

Section: Impact Of Insomnia On Men With Prostate Cancer Hrqolmentioning

confidence: 99%

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Are we sleeping on the job? Insomnia among men with prostate cancer

Drummond

2016

Adv Mod Oncol Res

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Prostate cancer is one of the most commonly diagnosed cancers in men and almost half of male cancer survivors in the US have had a prostate cancer diagnosis. Insomnia is common among cancer patients and survivors. There is evidence that cognitive behavioural therapy can be used to effectively manage insomnia among women with breast cancer. The aim of this review was to investigate the prevalence, risk factors and management of insomnia among men with prostate cancer. The effect of insomnia on the psychological health and health-related quality of life of these patients and/or survivors is also discussed. Increased awareness and knowledge of this symptom among men with prostate cancer may facilitate improved diagnosis, and management of insomnia in this large population. This in turn may improve the health-related quality of life of these men. Therefore, research into the effective management of insomnia among men with prostate cancer is essential.Keywords: prostate cancer; insomnia; androgen deprivation therapy; radiotherapy; health-related quality of life; depression; anxiety

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Section: Insomnia and Different Cancer Sitesmentioning

confidence: 99%

Section: Impact Of Insomnia On Men With Prostate Cancer Hrqolmentioning

confidence: 99%

Are we sleeping on the job? Insomnia among men with prostate cancer

Drummond

2016

Adv Mod Oncol Res

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“…The use of IMRT significantly reduced the risk of late grade 2 or higher gastrointestinal (GI) toxicity to 5% compared to 13% with 3D-CRT. [84]. HDR brachytherapy as monotherapy has been pioneered in a small number of centres with low published toxicity and high biochemical control rates, but currently mature data is not available on the optimal treatment schedule [85].…”

Section: Side Effects Of Definitive Radiotherapymentioning

confidence: 99%

EAU-ESTRO-SIOG Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent

et al. 2017

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“…Such amplification can be done by several different methods: threedimensional conformal radiotherapy, intensity-modulated radiotherapy and combinations of these approaches with high-dose-rate brachytherapy (HDRBT), low-dose-rate brachytherapy or particle beam boosts. Some studies have compared acute effects of traditional and modern doseescalated radiotherapy on HRQoL in PC patients (6,7), and the results indicated comparable HRQoL outcomes. However, few investigations have examined long-term effects in this clinical context.…”

Section: Introductionmentioning

confidence: 99%

Long-term health-related quality of life after curative treatment for prostate cancer: A regional cross-sectional comparison of two standard treatment modalities

Hjälm-Eriksson

Lennernäs

Ullén

et al. 2014

International Journal of Oncology

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Abstract. Effects on long-term health-related quality of life (HRQoL) were evaluated in patients treated for localized prostate cancer by two standard modalities: radical retropubic prostatectomy (RP) and external beam radiotherapy combined with a high-dose-rate brachytherapy boost (HDRBT-EBRT). The HRQoL data were compared with age-adjusted normative data. Men diagnosed with localized prostate cancer and treated with curative intent in Gothenburg, Sweden, 1988Sweden, -1997 were included. HRQoL was measured in October 2000 using the EORTC QLQ-C30 and EORTC QLQ-PR25 questionnaires, with a response rate of 82% (n=347). No differences in patient characteristics were found between the two treatment groups, except regarding tumor stage and PSA recurrence at the time of the questionnaires. In the RP group, 42% had T1 and 6% had T3-4 tumors; corresponding proportions in the HDRBT-EBRT group were 29% and 13% (P=0.01). PSA recurrence was detected in 44% of RP patients and 9% of HDRBT-EBRT patients. In most domains, mean HRQoL scores were high and similar to the scores for the age-adjusted normative sample. However, patients reported better role and physical function compared to the normal population. We also observed more sleeping disturbances but less pain among patients than in the normal population. The disease-specific questionnaires showed statistically significant higher levels of bowel and urinary problems in the irradiated group than in the RP group, and the absolute difference between the groups was small and had minor clinical significance. We conclude that overall the general quality of life was rated high by the patients irrespective of curative treatment modality and in agreement with age-adjusted normative data. Statistically significant differences in bowel and urinary symptoms were found between the two treatment groups in favor of the RP group, but the clinical significance was small.

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3-D conformal treatment of prostate cancer to 74 Gy vs. high-dose-rate brachytherapy boost: A cross-sectional quality-of-life survey

Abstract: (2006) 3-D conformal treatment of prostate cancer to 74 Gy vs. high-dose-rate brachytherapy boost: A cross-sectional quality-of-life survey, Acta Oncologica, 45:6,[708][709][710][711][712][713][714][715][716]

Cited by 22 publications

References 25 publications

Are we sleeping on the job? Insomnia among men with prostate cancer

Are we sleeping on the job? Insomnia among men with prostate cancer

EAU-ESTRO-SIOG Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent

Long-term health-related quality of life after curative treatment for prostate cancer: A regional cross-sectional comparison of two standard treatment modalities

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