3 - Bariatric Surgery is Safe in Patients with Compensated Cirrhosis – An Update on Outcomes from 2008–2013

Cost-effectiveness Analysis of Bariatric Surgery for Patients With Nonalcoholic Steatohepatitis Cirrhosis

“…In addition, a recent analysis found no association between compensated cirrhosis and increased mortality in patients undergoing bariatric surgery, suggesting that our analysis may even overstate the dangers of bariatric surgery. 41 Our findings are consistent with the available evidence, suggesting that bariatric surgery offers an acceptably low risk in patients with compensated cirrhosis, potentially even in those with portal hypertension. 42,43 To date, no clinical studies have compared outcomes of SG and GB in patients with NASH cirrhosis.…”

“…In sensitivity analyses, surgery remained cost-effective in patients with obesity, including those with mild obesity (BMI, 30.0-35.0), even when we assumed a small benefit of weight loss on liver disease progression and an increase in the the risk of surgical mortality. In addition, a recent analysis found no association between compensated cirrhosis and increased mortality in patients undergoing bariatric surgery, suggesting that our analysis may even overstate the dangers of bariatric surgery . Our findings are consistent with the available evidence, suggesting that bariatric surgery offers an acceptably low risk in patients with compensated cirrhosis, potentially even in those with portal hypertension …”