Telemedicine and Teledermatology 2002
DOI: 10.1159/000067377
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3.5. Potential of Telemedicine in Primary Care

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“…Autoantibodies such as anti-DNA and anti-RNP can penetrate into living cells and interact with their intracellular and nuclear targets. [11][12][13][14] Some of these autoantibodies possess multiple positively charged amino acids in the complementarity determining region 3 of H chain (CDR3H) in a sequence that resembles a nuclear localization signal. 15 Several studies have demonstrated that the cell penetrating Abs can induce tumor cell death.…”
Section: Introductionmentioning
confidence: 99%
“…Autoantibodies such as anti-DNA and anti-RNP can penetrate into living cells and interact with their intracellular and nuclear targets. [11][12][13][14] Some of these autoantibodies possess multiple positively charged amino acids in the complementarity determining region 3 of H chain (CDR3H) in a sequence that resembles a nuclear localization signal. 15 Several studies have demonstrated that the cell penetrating Abs can induce tumor cell death.…”
Section: Introductionmentioning
confidence: 99%