3,3′-di[1,3-thiazolidin-4-one] system. Structural and conformational studies on configurational isomers with anti-inflammatory activity

Crystal structures of two 1,3-thiazolidin-4-one derivatives featuring sulfide and sulfone functional groups

“…Bond length and angle values in the thiazolidinone ring of the sulfide appear to be typical and match data that we have previously reported (Nuriye et al, 2018). Although structural data for the sulfone are scarce, the data reported by Orsini et al (1995) matches our findings.…”

“…The synthesis and characterization of these compounds could be valuable in investigations for the practical applications of their activities. To the best of our knowledge, only two crystal structures of thiazolidinone sulfones have been reported in the literature (Orsini et al, 1995;Glasl et al, 1997). The compounds presented in this paper both feature an ortho-nitrophenyl ring at position 2 and a cyclohexane ring at the 3-position of the thiazolidinone ring.…”

Synthesis, characterization, antibacterial and antifungal activity of 2‐(aryl)‐3‐(3‐((8‐hydroxyquinolin‐5‐yl)diazenyl)phenyl)thiazolidin‐4‐ones

“…4‐Thiazolidinone derivatives exhibit broad spectrum of biological activity [ 33–36]. Its derivatives have been found to have potentially chemotherapic activities such as anticonvulsant [ 37], antibacterial [ 38], antifungal [ 39], anti‐inflammatory [ 40], anticancer [ 41], and antipsychotic [ 42] properties. Some of the reported 4‐thiazolidinones have showed envelope or half‐chair conformation with different configurations [ 43].…”