3-[2-(8-Quinolinyl)benzoxazol-5-yl]alanine derivative—a specific fluorophore for transition and rare-earth metal ion detection

3-[2-(2-Quinoxalinyl)benzoxazol-5-yl]alanine derivative – A specific fluoroionophore for Ni(II)

“…The insertion of the strong coordination centres into amino acids or peptide enables the construction of supramolecules, which may play role in molecular recognitions [1,2]. This objective can be reached by coupling the amino acid or peptide with a crown ether, in which the cavity size can be changed to fit the metal ion diameter.…”

“…This objective can be reached by coupling the amino acid or peptide with a crown ether, in which the cavity size can be changed to fit the metal ion diameter. Apart from crown ether based chemoionophores, the oldest class of chemo/fluoroionophore molecules are the fluorescent ligands which are mostly heteroaromatic ring systems often substituted by potentially chelating groups which act as both the recognition and signalling site [2,3]. N,N-bidentate ligands play an important role as molecular sensors, DNA intercalators [3], photovoltaics [4] because they are capable to chelate various metal ions and their complexes possess diversified photophysical and electrochemical properties.…”

“…In this paper, we describe a new chemoionophore containing a quinoxaline moiety appended to position 2 of 3-(benzoxazol-5-yl)alanine ( Fig. 1) which is a representative of a group of new aromatic amino acids whose spectral and photophysical properties can be modified by changing a substituent in position 2 [2,[10][11][12][13][14][15].…”

Evidence for the 310‐helical structure of peptides based on antAib, a fluorophoric, anthracene‐fused, 1‐aminocyclopentane‐1‐carboxylic acid

“…This conclusion is corroborated by a comparison between the spectra of 5a and 5 0 a (the former not shown), which clearly indicates that the pentapeptide with two antAib residues (5a) is much more extensively H-bonded than that with only one antAib (5 0 a). Notably, the terminally-protected (L-Ala) 5,6 homo-oligomers strongly self-aggregate under these experimental conditions. 20 This vibrational spectroscopic analysis allows us to conclude that the longer oligomers of this series are folded in an ordered secondary structure stabilized by a set of intramolecular C¼ ¼O Á Á Á HÀ ÀN H-bonds.…”

Dye‐Labeled Cα‐Tetrasubstituted α‐Amino Acids

“…Some representative examples are depicted in Fig. 1: 3-[2-(quinolin-8-yl)benzoxazol-5-yl]alanine derivatives [38], phthalimide based amino acids [39], different substituted coumaryl analogs [40], or acridin-9(10H)-one moieties, a -d, respectively [41]. Suhartono et al described the linkage of pyrene and other aromatics by Pd-catalyzed Heck reaction to b,gunsaturated and protected amino acids, which were obtained via known side-chain transformation of methionine e [42].…”