2SD1025 Quantifying the Escherichia coli proteome and transcriptome in a single cell with single-molecule sensitivity(2SD Bridging Single Molecule Biophysics and System Biology:New Experimental and Theoretical Challenges,The 48th Annual Meeting of the Biophysical Society of Japan)

Abstract

Howes er the low sensiti"ty elnd short hfe time ol the sampleg had so far pre vented the acqllsmon of suMcient structural mformat]on to determme protem gtmctureg by in cel] NMR Recentlv we reported the first 3D protem structure calculated exctuyvely on the basis of mformatson obtained ]i 1"mg E colt cells The m v"o structures