Untitled

Kapoor, Tarun M.; Gutiérrez, Guillermo

doi:10.1186/cc2362

Cited by 36 publications

(7 citation statements)

References 17 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, according to a case report, air embolism has been noted as the cause of endothelium-derived cytokine release, leading to initiation of the systemic inflammatory response [10]. …”

Section: Discussionmentioning

confidence: 99%

Air Embolism: Diagnosis, Clinical Management and Outcomes

et al. 2017

View full text Add to dashboard Cite

Air embolism is a rare but potentially fatal complication of surgical procedures. Rapid recognition and intervention is critical for reducing morbidity and mortality. We retrospectively characterized our experience with air embolism during medical procedures at a tertiary medical center. Electronic medical records were searched for all cases of air embolism over a 25-year period; relevant medical and imaging records were reviewed. Sixty-seven air embolism cases were identified; the mean age was 59 years (range, 3–89 years). Ninety-four percent occurred in-hospital, of which 77.8% were during an operation/invasive procedure. Vascular access-related procedures (33%) were the most commonly associated with air embolism. Clinical signs and symptoms were related to the location the air embolus; 36 cases to the right heart/pulmonary artery, 21 to the cerebrum, and 10 were attributed to patent foramen ovale (PFO). Twenty-one percent of patients underwent hyperbaric oxygen therapy (HBOT), 7.5% aspiration of the air, and 63% had no sequelae. Mortality rate was 21%; 69% died within 48 hours. Thirteen patients had immediate cardiac arrest where mortality rate was 53.8%, compared to 13.5% (p = 0.0035) in those without. Air emboli were mainly iatrogenic, primarily associated with endovascular procedures. High clinical suspicion and early treatment are critical for survival.

show abstract

Section: Discussionmentioning

confidence: 99%

Air Embolism: Diagnosis, Clinical Management and Outcomes

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Traveling in systemic arteries, the air bubbles can occlude blood vessels to cause ischaemic end-organ damage. Furthermore, the systemic inflammatory response syndrome has also been reported as a result of the interaction between air emboli and arterial endothelium [ 24 ].…”

Section: Pathophysiology and Clinical Manifestationsmentioning

confidence: 99%

Venous air embolism related to the use of central catheters revisited: with emphasis on dialysis catheters

Wong¹,

Kwaan²,

Ing³

2017

Clinical Kidney Journal

View full text Add to dashboard Cite

Venous air embolism is a dreaded condition particularly relevant to the field of nephrology. In the face of a favourable, air-to-blood pressure gradient and an abnormal communication between the atmosphere and the veins, air entrance into the circulation is common and can bring about venous air embolism. These air emboli can migrate to different areas through three major routes: pulmonary circulation, paradoxical embolism and retrograde ascension to the cerebral venous system. The frequent undesirable outcome of this disease entity, despite timely and aggressive treatment, signifies the importance of understanding the underlying pathophysiological mechanism and of the implementation of various preventive measures. The not-that-uncommon occurrence of venous air embolism, often precipitated by improper patient positioning during cervical catheter procedures, suggests that awareness of this procedure-related complication among health care workers is not universal. This review aims to update the pathophysiology of venous air embolism and to emphasize the importance of observing the necessary precautionary measures during central catheter use in hopes of eliminating this unfortunate but easily avoidable mishap in nephrology practice.

show abstract

“…One study reported that VAE induces platelet dysfunction and thrombocytopenia [ 29 ]. A study with animals revealed that platelet aggregation and the release of plasminogen-activator inhibitors can be a result of the formation of microbubbles [ 30 ]. In our case, the reason for intraoperative coagulopathy might have been hypovolemia, although fluid resuscitation is limited in LT patients, especially during the dissection phase.…”

Section: Discussionmentioning

confidence: 99%

Disseminated intravascular coagulation following air embolism during orthotropic liver transplantation: is this just a coincidence?

Arstikyte

Vitkute

Traškaitė-Juškevičienė

et al. 2021

BMC Anesthesiol

View full text Add to dashboard Cite

Background During orthotopic liver transplantation, venous air embolism may occur due to iatrogenic injury of the inferior vena cava. However, venous air embolism followed by coagulopathy is a rare event. In this case report, we discuss a possible connection between venous air embolism and disseminated intravascular coagulation. Case presentation A 37-year-old male patient with chronic hepatitis B- and C-induced liver cirrhosis was admitted for orthotopic liver transplantation. During the dissection phase of the surgery, arterial blood pressure, heart rate, saturation and end-tidal carbon dioxide levels suddenly decreased, indicating the occurrence of venous air embolism. After stabilizing the patient’s condition, various coagulation issues started developing. Venous air embolism-induced coagulopathy was handled by administering transfusions of various blood products. However, the patient’s condition continued to deteriorate leading to a complete asystole. Conclusions This is a rare case of venous air embolism-induced disseminated intravascular coagulation. The real connection remains unclear as disseminated intravascular coagulation for end-stage liver disease patients can be induced by various causes during different stages of liver transplantation. Certainly, both venous air embolism and coagulopathy were significant and led to an unfavorable outcome. Further studies are needed to better understand the possible mechanisms and correlation between these two life-threatening complications.

show abstract

Untitled

Cited by 36 publications

References 17 publications

Air Embolism: Diagnosis, Clinical Management and Outcomes

Air Embolism: Diagnosis, Clinical Management and Outcomes

Venous air embolism related to the use of central catheters revisited: with emphasis on dialysis catheters

Disseminated intravascular coagulation following air embolism during orthotropic liver transplantation: is this just a coincidence?

Contact Info

Product

Resources

About