2nd PCA on 3D protein structure similarity

An Exhaustive Shape-Based Approach for Proteins' Secondary, Tertiary and Quaternary Structures Indexing, Retrieval and Docking

“…It should be noted that the carbon atoms provide a very low resolution representation of the shape of the macromolecule. This approach has been extended by (Chen et al, 2010). They propose to analyze the texture associated with the distance matrix in terms of principal component analysis (PCA).…”