2nd ESMO Consensus Conference on Lung Cancer: early-stage non-small-cell lung cancer consensus on diagnosis, treatment and follow-up

Pulmonary function and quality of life after VMAT-based stereotactic ablative radiotherapy for early stage inoperable NSCLC: a prospective study

“…Stereotactic Ablative Radiotherapy (SABR) is currently recognized as the gold standard for patients with inoperable stage I non-small cell lung cancer (NSCLC) [1]. This recommendation is based on the results of several prospective phase II trials [2], [3], [4], [5] and [6], as well as large observational studies [7], [8] and [9], with variable follow-up intervals: most of them were limited to spirometric parameters and diffusing capacity for carbon monoxide (Diffusion Lung capacity for Carbon monoxide, D L CO).…”

Thermal Ablation of Lung Tumors: Focus on Microwave Ablation

“…Given the better local control rates, the treatment of choice for stage I NSCLC is considered to be either open or video-assisted thoracic surgery [88]. However, in the case of patients with early-stage NSCLC and severely impaired lung function, a local ablative therapy (SBRT or RFA) can be considered [89].…”

Salvage surgery after high-dose radiotherapy

“…In the recently introduced 8th TNM edition further subdivisions are made in the T (tumor) descriptor with increments of 1 cm for T1 and T2 lung cancer, as prognosis is best for the smallest lung cancers (5). According to the guidelines of the European Society of Medical Oncology (ESMO) lobectomy is still considered the standard surgical treatment for early-stage lung cancer (6). In patients who are unable to undergo a lobectomy, but fit for surgery, sublobar resections represent an alternative option and are preferred over radiotherapy (7,8).…”