2D and 3D dose analysis of PRESAGE® dosimeter using a prototype 3DmicroHD-OCT imaging system

Mohyedin, Muhammad Zamir; Zin, Hafiz M.; Hashim, Suhairul; Bradley, D.A.; Aldawood, S.; Alkhorayef, M.; Sulieman, Abdelmoneim; Rahman, Ahmad Taufek Abdul

doi:10.1016/j.radphyschem.2022.110312

Cited by 5 publications

(3 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The characterisation of the 3DmicroHD-OCT shows excellent dose linearity and dose rate independency of the PRESAGE®. In addition, the percentage depth dose (PDD) pro le measured from the system has a good agreement with the PDD pro le from an ionisation chamber (Mohyedin, Zin, Hashim, et al, 2022). The feasibility study of the system shows the system is capable to visualise SRS treatment dose distribution in a homogenous condition .…”

Section: Introductionmentioning

confidence: 71%

See 1 more Smart Citation

Study of PRESAGE® dosimeter for end-to-end 3D radiotherapy verification using an anthropomorphic phantom with bespoke dosimeter insert

Mohyedin,

Zin,

Abubakar

et al. 2024

Phys Eng Sci Med

Self Cite

View full text Add to dashboard Cite

Modern radiotherapy techniques have advanced and become more sophisticated. End-to-end 3D veri cation of the complex radiotherapy dose distribution in an anthropomorphic phantom is important to ensure the accuracy of the treatment delivery. The phantoms typically used are homogenous waterequivalent phantoms and lack of capability to measure the dose in 3D. Therefore, we developed an endto-end 3D radiotherapy dose veri cation system based on MAX-HD anthropomorphic phantom (IMT, Troy, New York) with bespoke intracranial insert for PRESAGE® dosimeter. In this study, several radiotherapy treatment techniques of various levels of complexity, 3D-CRT, IMRT and SRS treatment, were planned for a 20 mm diameter of a spherical target in the brain region and delivered to the phantom. The dosimeters were read out using an in-house optical computed tomography (OCT) imaging system known as 3DmicroHD-OCT. It was found that the measured dose distribution of the PRESAGE® shows good agreement with the measured dose distribution of EBT lm and Monaco TPS with a maximum difference of less than 3% from 3D-CRT, IMRT and SRS treatment planning. The gamma analysis results of PRESAGE® in comparison to EBT lm and Monaco TPS show pass rates of more than 95% for the criteria of 3% dose difference and 3 mm distance-to-agreement. This study proves the capability of PRESAGE® and bespoke MAX-HD phantom in conjunction with the 3DmicroHD-OCT system to measure 3D dose distribution for end-to-end dosimetry veri cation.

show abstract

Section: Introductionmentioning

confidence: 71%

“…The matching liquid is a mix of 45% of 2-ethylhexyl salicylate and 55% of 2-ethylhexyl 4-methoxycinnamate and is ltered before being used to remove any suspended foreign objects. The detailed developments of the scanner can be read elsewhere (Mohyedin, Zin, Hashim, et al, 2022).…”

Section: The Scanning Of the Dosimetermentioning

confidence: 99%

Study of PRESAGE® dosimeter for end-to-end 3D radiotherapy verification using an anthropomorphic phantom with bespoke dosimeter insert

Mohyedin,

Zin,

Abubakar

et al. 2024

Phys Eng Sci Med

Self Cite

View full text Add to dashboard Cite

show abstract

“…A CMOS-OCT system has been developed as a measurement in radiotherapy [ 35 , 138 ]. A study demonstrated that a CMOS-OCT was able to produce a multidimensional dose analysis with consistent results [ 139 ]. The CMOS-OCT system was also capable of visualising stereotactic radiosurgery (SRS) treatment dose distribution in a PRESAGE dosimeter.…”

Section: Readout Modalitiesmentioning

confidence: 99%

A Review of PRESAGE Radiochromic Polymer and the Compositions for Application in Radiotherapy Dosimetry

et al. 2022

Self Cite

View full text Add to dashboard Cite

Recent advances in radiotherapy technology and techniques have allowed a highly conformal radiation to be delivered to the tumour target inside the body for cancer treatment. A three-dimensional (3D) dosimetry system is required to verify the accuracy of the complex treatment delivery. A 3D dosimeter based on the radiochromic response of a polymer towards ionising radiation has been introduced as the PRESAGE dosimeter. The polyurethane dosimeter matrix is combined with a leuco-dye and a free radical initiator, whose colour changes in proportion to the radiation dose. In the previous decade, PRESAGE gained improvement and enhancement as a 3D dosimeter. Notably, PRESAGE overcomes the limitations of its predecessors, the Fricke gel and the polymer gel dosimeters, which are challenging to fabricate and read out, sensitive to oxygen, and sensitive to diffusion. This article aims to review the characteristics of the radiochromic dosimeter and its clinical applications. The formulation of PRESAGE shows a delicate balance between the number of radical initiators, metal compounds, and catalysts to achieve stability, optimal sensitivity, and water equivalency. The applications of PRESAGE in advanced radiotherapy treatment verifications are also discussed.

show abstract

Measurement of the radiation dose and radiation isocenter of the TrueBeam accelerator using 3D polymer gel dosimeters from the VIPAR family with different chemical history

et al. 2023

View full text Add to dashboard Cite

2D and 3D dose analysis of PRESAGE® dosimeter using a prototype 3DmicroHD-OCT imaging system

Cited by 5 publications

References 26 publications

Study of PRESAGE® dosimeter for end-to-end 3D radiotherapy verification using an anthropomorphic phantom with bespoke dosimeter insert

Study of PRESAGE® dosimeter for end-to-end 3D radiotherapy verification using an anthropomorphic phantom with bespoke dosimeter insert

A Review of PRESAGE Radiochromic Polymer and the Compositions for Application in Radiotherapy Dosimetry

Measurement of the radiation dose and radiation isocenter of the TrueBeam accelerator using 3D polymer gel dosimeters from the VIPAR family with different chemical history

Contact Info

Product

Resources

About