2D:4D finger length ratio and radiographic hand osteoarthritis

Kalichman, Leonid; Batsevich, Valery; Kobyliansky, Eugene

doi:10.1007/s00296-017-3831-1

Cited by 9 publications

(11 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some previous studies reported an association between morbidity and type 3 finger length ratio. For example, in our previous study, we found a significant association between finger length ratio and skeletal aging in a nonlongevity sample of Chuvashians (Kalichman et al, 2017a(Kalichman et al, , 2017b. Females with a type 3 (prenatally more androgenized) finger length pattern showed significantly higher hand osteoarthritis and osseographic score (an index of biological aging) values than those with types 1 and 2.…”

Section: Discussionmentioning

confidence: 74%

“…One examiner performed visual comparison of the soft tissue outline of the finger ends on the radiograph (Robertson et al, ; Zhang et al, ). The method was described in detail in previous publications (Kalichman et al, , ).…”

Section: Methodsmentioning

confidence: 99%

“…Finger length ratio is a predictor of disease predisposition (Manning & Bundred, 2000), and was found to be associated with age-related parameters such as bone mineral density (Arazi, Eghbali, Saeedi, & Moghadam, 2016) and skeletal biomarkers of biological aging (Kalichman, Batsevich, & Kobyliansky, 2017b). A low ratio, 2D < 4D, or more androgenized, finger length ratio/pattern (type 3) was significantly associated with osteoarthritis (de Kruijf et al, 2014;Ferraro, Wilder, & Leaverton, 2010;Hussain et al, 2014;Kalichman, Batsevich, & Kobyliansky, 2017a;Sigurjonsdottir et al, 2013;Zhang et al, 2008). Sigurjonsdottir et al (Sigurjonsdottir et al, 2013) found that the type 3 finger ratio was associated with total knee, but not with a total hip replacement.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Finger length ratio in longevity populations

Kalichman

Batsevich

Kobyliansky

2019

American J Hum Biol

Self Cite

View full text Add to dashboard Cite

Objectives The purpose of this study was to compare the prevalence of finger length ratio between three longevity populations (Abkhazians, Azerbaijanis, and Georgians) and one nonlongevity population (Russians), as well as between a longevity and nonlongevity sample within one ethnic group (Abkhazians). Methods In a cross‐sectional observational study, we compared the prevalence of finger length ratio in longevity vs nonlongevity samples. Results A negative relationship was observed between longevity index and prevalence of type 1 (feminine type) ratio. In longevity samples, the prevalence of type 1 ratio was lower and the prevalence of type 3 (masculine type) ratio was higher than in the nonlongevity sample of Russians. This difference was statistically significant (P < .001) in both males and females. A similar difference between longevity and nonlongevity samples was exhibited in the Abkhazian samples. In males and females, a significantly higher prevalence of type 1 and lower type 3 finger ratios (P < .001) were shown in the nonlongevity samples. Conclusions Finger length ratio pattern in longevity populations differs from that of nonlongevity populations. In longevity samples, the prevalence of type 1 ratio was lower and the prevalence of type 3 ratio was higher vs the nonlongevity sample. A similar type of difference was seen in the longevity and nonlongevity samples belonging to one ethnic group, the Abkhazians. Previous studies found that the type 1 finger length ratio was related to important morbidities that have a potential for shortening the life span. This can be one of the most plausible explanations for our findings.

show abstract

Section: Discussionmentioning

confidence: 74%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Finger length ratio in longevity populations

Kalichman

Batsevich

Kobyliansky

2019

American J Hum Biol

Self Cite

View full text Add to dashboard Cite

show abstract

“…Osteoarthrosis may develop in the long bone with aging according to the indication a reviewer. However, the transformation of the bone of the finger is not caused other than the special diseases such as rheumatism, amyotrophic lateral sclerosis (ALS) or the hyperparathyroidism (Kalichman et al 2018;Zhang W et al 2008, Parkin Kullmann and Pamphlett, 2017, Rhara et al 2015. In this study, effective points with the using short bone such as the finger include that there is little osteoarthrosis.…”

Section: Discussionmentioning

confidence: 99%

Forensic evaluation of sex estimation via measurements of adult index and ring finger lengths using postmortem computed tomography

Ikeda

Miyamoto²,

Tani

et al. 2018

Egypt J Forensic Sci

View full text Add to dashboard Cite

Background: Sex estimation from fragmented or isolated human bones found during excavations is imperative not only in the field of forensics but also paleoanthropology. This study investigated the possibility of sex estimation from computed tomography (CT) data for the lengths of the index and ring fingers. The scans were obtained using a multislice ECLOS-16 CT scanner (Hitachi Medical Co., Tokyo, Japan), and the images were analyzed using a SYNAPSE VINCENT volume analyzer (Fujifilm Medical Co., Tokyo, Japan). For 205 cases, the authors measured the total length of the distal, middle, and proximal phalanges (P) and of the metacarpal bones for the index and ring fingers of both hands. Right heart serum testosterone and estradiol levels in 92 cases were also measured by an electrochemiluminescence immunoassay and a chemiluminescence immunoassay, respectively. Result: The difference in P between the index and ring fingers was significantly greater in men than in women for both hands; receiver operating characteristic analysis showed an optimal cutoff of 6.0 mm (sensitivity, 0.64 and specificity, 0.64). Blood testosterone levels were moderately correlated with this difference. Conclusion: A value of 6.0 mm for the ring finger-index finger difference for the left hand distinguished men from women, and these results are affected by testosterone levels. The findings from this report in the field of forensics and paleoanthropology indicated that the CT data-assessed morphometry of the phalanges could be used as an objective index for sex estimation.

show abstract

“…We measured index and ring finger lengths from the right and left forelimb hands in both groups after the last day of behavioral data acquisition using a digital radiography unit with a flat-panel digital detector (PLX8200, Perlove, Nanjing, China) (Kalichman et al, 2017). The digital detector was exposed to X-ray at 60 kVp, with an approximate detector-to-tube distance of 1 m. Exposure times were no greater than 0.1 s, resulting in 4.0 mA exposure.…”

Section: Methodsmentioning

confidence: 99%

Depressed female cynomolgus monkeys (Macaca fascicularis) display a higher second-to-fourth (2D:4D) digit ratio

Li¹,

Luo

Yang

et al. 2019

Zoological Research

View full text Add to dashboard Cite

This research aimed to provide evidence of a relationship between digit ratio and depression status in the cynomolgus monkey ( Macaca fascicularis ). In stable cynomolgus monkey social groups, we selected 15 depressed monkeys based on depressive-like behavioral criteria and 16 normal control monkeys. All animals were video recorded for two weeks, with the duration and frequency of the core depressive behaviors and 58 other behaviors in 12 behavioral categories then evaluated via behavioral analysis. Finger lengths from the right and left forelimb hands of both groups were measured by X-ray imaging. Finger length and digit ratio comparisons between the two groups were conducted using Student’s t -test. In terms of the duration of each behavior, significant differences emerged in “Huddling” and five other behavioral categories, including Ingestive, Amicable, Parental, Locomotive, and Resting. In addition to the above five behavioral categories, we found that depressed monkeys spent less time in parental and rubbing back and forth behaviors than the control group. Furthermore, the 4th fingers were significantly longer in the left and right hands in the control group relative to the depressed monkeys. The second-to-fourth (2D:4D) digit ratio in the left and right forelimb hands was significantly lower in the control group than that in the depressed group. Our findings revealed significant differences in finger lengths and digit ratios between depressed monkeys and healthy controls, which concords with our view that relatively high fetal testosterone exposure may be a protective factor against developing depressive symptoms (or that low fetal testosterone exposure is a risk factor).

show abstract

2D:4D finger length ratio and radiographic hand osteoarthritis

Cited by 9 publications

References 28 publications

Finger length ratio in longevity populations

Finger length ratio in longevity populations

Forensic evaluation of sex estimation via measurements of adult index and ring finger lengths using postmortem computed tomography

Depressed female cynomolgus monkeys (Macaca fascicularis) display a higher second-to-fourth (2D:4D) digit ratio

Contact Info

Product

Resources

About