Untitled

Abstract

Background: Main of agriculturists in Singburi was cultivated rice and major pesticides' use is chlorpyrifos; however, farmers are applied bio-extracts to eliminate pest and trend to be organic farming. Hence, organic farmers may become lower risks from pesticides rather than non-organic farmers. Aim: To determine biochemical and hematological status between organic and non-organic farmers, Bang Rachan district, Singburi, Thailand. Materials and Methods: Farmers were separated into organic farmer group (N = 35) and non-organic farmer group (N = 45). Individual data for pesticide exposure were included, and pesticide-exposed relating symptoms were recorded. All demographic data of participants were documented before blood collection. Serum samples were analyzed for butyrylcholinesterase (BuChE) activity, liver function test, kidney function test, and lipid profiles. Each ethylenediaminetetraacetic acid-whole blood was determined for complete blood count (CBC). NaF plasma was analyzed for determine fasting blood glucose. All biochemical parameters were principled according to enzymatic assays and CBC was automatic analyzers. The data were represented in average ± standard deviation, and difference of biochemical and hematological status of two groups was statistically tested by unpaired t-test (P < 0.05). Results and Discussion: Blood glucose and lipid profiles of non-organic farmers were higher than reference ranges and significantly difference with other groups. Mean corpuscular hemoglobin (MCH) and MCH concentration values of non-organic farmers were lower than reference range and interpreted as anemia. Conclusions: Non-organic farmers were suchronic pesticide exposure with normal BuChE values and no related symptom; therefore, subclinical symptoms were disturbed biochemical and hematological status; and prediabetes, dyslipidemia, and anemia appeared.

Oxidative Stress Indices of Organophosphates Pesticides Among Agricultural Workers at Mit-Ghamr District, Egypt

“…The present study revealed that SOD was significantly lower among exposed group compared to non-exposed group, (p-value = 0.000) (table 1), this is in agreement with Vidyasagar et al who reported that RBC SOD was lower among exposed versus control group [25]. Other studies in India and Egypt showed the same reduction in the SOD activity in the exposed groups [19][20][21][22][23][24][25][26]. In contrast to these results, some studies found an elevation of SOD levels in exposed group like Simoniello et al [30].…”

“…Also a lot of studies in Tunisia [17], Nigeria [9], Thiland [18] and India were in accordance with our results [19]. In contrast with this study, studies of Ogut et al [20] and Sudjaroen [21] didn't observe any statistical significant difference between both groups as regard BuChE levels. This contrast may be as a result of different levels of exposure in different countries due to usage of PPE or having washing facilities afire pesticides use.…”