Different clinical presentation of intralabyrinthine schwannomas – a systematic review

Elias, Thaís Gomes Abrahão; Neto, Adriana Perez Ferreira; Zica, Ana Tereza Silveira; Antunes, Marcos Luiz; Penido, Norma de Oliveira

doi:10.1016/j.bjorl.2018.05.007

Cited by 16 publications

(15 citation statements)

References 20 publications

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“…Hearing loss in various studies has been described as progressive, sudden, or fluctuating. 7,[16][17][18] Hearing loss is mainly sensorineural; however, mixed hearing loss has been described and is thought to be from inner ear conductive loss caused by blockage of inner ear fluid movement by tumor. 11,19 Tinnitus is the next most common presenting symptom with studies showing a range of 69.1 to 95.8% of patients with tinnitus, 10.5% being pulsatile tinnitus.…”

Section: Biology and Presentation Of Intralabyrinthine/ Intracochlearmentioning

confidence: 99%

“…6 Various studies have shown that the IC schwannomas are more common than the other types, representing 50% or greater of cases. 6,7 Intravestibular types and ILS that extend outside of the labyrinth make up 19% and mixed vestibulocochlear types comprise 11.8%. TO cases are the least common, with 2 of 45 (4.4%) cases reported in one study.…”

Section: Classificationmentioning

confidence: 99%

“…[3][4][5] They are rare tumors, with only 526 described in the literature to date and present with many of the same symptoms of other pathologic processes such as vertigo, dizziness, tinnitus, and hearing loss. 6,7 With the advent of magnetic resonance imaging (MRI) and improvements in imaging technology over time, diagnosis has become more prevalent. [8][9][10][11][12][13] These tumors can present an interesting therapeutic challenge given their benign nature, location, and symptomatology.…”

Section: Introductionmentioning

confidence: 99%

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Intralabyrinthine Schwannomas: Disease Presentation, Tumor Management, and Hearing Rehabilitation

2019

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Intralabyrinthine schwannomas (ILS) are rare tumors that frequently cause sensorineural hearing loss. The development and increased use of magnetic resonance imaging in recent years have facilitated the diagnosis of these tumors that present with otherwise nondiscriminant symptoms such as tinnitus, vertigo, and hearing loss. The following is a review of the presentation, pathophysiology, imaging, and treatment with a focused discussion on auditory rehabilitation options of ILS.

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Section: Biology and Presentation Of Intralabyrinthine/ Intracochlearmentioning

confidence: 99%

Section: Classificationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Intralabyrinthine Schwannomas: Disease Presentation, Tumor Management, and Hearing Rehabilitation

2019

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“…The clinical presentation of IAC VS produces a combination of otologic signs and symptoms with unilateral, progressive hearing loss one of the most common at presentation (95%). The less commonly reported resulting symptoms include tinnitus, imbalance, vertigo, and aural fullness which can present alone or in combination with one another [3]. Sudden SNHL is an exceedingly rare clinical presentation for ICS which has been minimally reported in the literature regarding this topic.…”

Section: Introduction/backgroundmentioning

confidence: 99%

Unusual presentation of an intracochlear schwannoma

Holmes¹,

Watson²,

Babin³

et al. 2021

J Clin Images Med Case Rep

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In this report, the authors discuss the case of a 49-year-old male presenting with sudden onset moderately severe left-sided Sensorineural Hearing Loss (SNHL), tinnitus, left otalgia, and disequilibrium. Prior to referral to our facility, an MRI was obtained which demonstrated non-specific asymmetric enhancement of the left cochlea that was initially suspected to be labyrinthitis. Patient was treated with valacyclovir and a prednisone burst-taper prior to referral. Despite this treatment, his left SNHL worsened, and he was noted to have left-sided peripheral weakness on Videonystagmography (VNG). Upon referral to our facility, MRI demonstrated an Intra-Cochlear Schwannoma (ICS), with possible associated hemorrhage into the cochlea. After discussion of treatment options, repeat imaging in 6-month interval demonstrated stable persistence of the lesion with no growth. The patient is currently being followed with a “Wait-andScan” regimen. Sudden unilateral SNHL is a rare presenting symptom for ICS and this case highlights not only the rarity in presentation, but also the complexity in diagnosis due to the possibility of intracochlear hemorrhage complicating the imaging work-up. Keywords: Intra-labyrinthine schwannoma; vestibular schwannoma; sensorineural hearing loss; disequilibrium. Abbreviations: SNHL: Sensorineural Hearing Loss; VNG: Videonystagmography; ICS: Intracochlear Schwannoma; MRI: Magnetic Resonance Imaging; IAC: Internal Auditory Canal; ILS Intra-Labyrinthine Schwannomas; CT: Computed Tomography; SRT: Speech Reception Threshold.

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“…Primary ILS are distinguished from Secondary ILS, the latter being developing from an extension of vestibular schwannoma (VS) through modiolus or macula. In primary ILS, Intracochlear schwannomas are more common than Intra vestibular schwannomas [1,2]. Kennedy et al [3] in 2004 classified ILS into 7 subtypes based on the anatomical extent, however, this was later modified in 2013 by Van Abel et al [1] renaming ILS to primary inner ear schwannomas (PIES) and adding 3 more subtypes (i) trans labyrinthine with tumors involving the vestibule, cochlea and IAC; (ii) ILS with extension into the CPA; and (iii) tumors not otherwise specified and to specify clear subsite categorization (Table 1).…”

Section: Introductionmentioning

confidence: 99%

Minimally invasive endoscopic removal of primary inner ear schwannomas

Mohammed

Jang

Han³

et al. 2021

Acta Oto-Laryngologica Case Reports

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Primary Inner Ear Schwannomas (PIES) are rare benign tumors. Due to their slow growth, they are often missed during initial screening evaluation, and thus diagnosis is often delayed. Careful analysis of history with scrutiny of MRI should help to differentiate them from other pathologies resembling in symptoms. Here, we presented 4 cases diagnosed with PIES and clinical characteristics of them were analyzed. Furthermore, we elaborated a new surgical approach for the treatment of 4 PIES cases, resulting in complete tumor removal with no evidence of recurrence or residual growth on postoperative MRI follow up. No major short-or long-term complications were noted. Our case series emphasizes on treatment of PIES through a Minimal Invasive Endoscopic approach avoiding incisions and mastoid drilling thereby reducing operative time and surgical morbidity.

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Different clinical presentation of intralabyrinthine schwannomas – a systematic review

Cited by 16 publications

References 20 publications

Intralabyrinthine Schwannomas: Disease Presentation, Tumor Management, and Hearing Rehabilitation

Intralabyrinthine Schwannomas: Disease Presentation, Tumor Management, and Hearing Rehabilitation

Unusual presentation of an intracochlear schwannoma

Minimally invasive endoscopic removal of primary inner ear schwannomas

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