Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial

Utility of robot‐assisted radical cystectomy with intracorporeal urinary diversion for muscle‐invasive bladder cancer

“…Local recurrence in the cystectomy bed was also similar in both groups (4% and 1%, respectively; P = 0.17) . No port site recurrences were reported . In a recent prospective randomized trial comparing RARC with ORC, there were no statistically significant differences between the groups, even though the ORC group tended toward higher overall rates of distant recurrence as their first site of recurrence than the RARC group (27.6% and 16.7%, respectively; P = 0.077) .…”

“…RARC is reported to increase the risk of peritoneal carcinomatosis, port site recurrences and extrapelvic lymph node metastases, which might be caused by tumor seeding associated with pneumoperitoneum, excessive manipulation of the cystectomy specimens and breach of the specimen bag . According to the Randomized Open versus Robotic Cystectomy trial, which was carried out to investigate whether RARC was non‐inferior to ORC for the treatment of BCa, the proportion of patients with local recurrences was similar between the RARC and ORC groups (4% and 3%, respectively; P = 0.54) . Local recurrence in the cystectomy bed was also similar in both groups (4% and 1%, respectively; P = 0.17) .…”

“…According to the Randomized Open versus Robotic Cystectomy trial, which was carried out to investigate whether RARC was non‐inferior to ORC for the treatment of BCa, the proportion of patients with local recurrences was similar between the RARC and ORC groups (4% and 3%, respectively; P = 0.54) . Local recurrence in the cystectomy bed was also similar in both groups (4% and 1%, respectively; P = 0.17) . No port site recurrences were reported .…”

Robot‐assisted radical cystectomy: Review of surgical technique, and perioperative, oncological and functional outcomes

“…ORC had a significantly shorter OT compared to RARC ( P < 0.01). Both groups showed similar complication rates …”

Editorial Comment to Utility of robot‐assisted radical cystectomy with intracorporeal urinary diversion for muscle‐invasive bladder cancer

“…They also showed the details of their surgical procedures of ICUD. RARC is currently being widely used in Japan since it has been covered by the national health insurance system, and the non‐inferiority of RARC compared with open radical cystectomy for 2‐year progression‐free survival was shown by a randomized trial . Because the surgical procedures of RARC are quite similar to those of robot‐assisted radical prostatectomy, which has already been established as a standard option for localized prostate cancer in Japan, RARC feels feasible for many urological surgeons.…”