Effects of Silicone Oil on Electrowetting to Actuate a Digital Microfluidic Drop on Paper

Cheong, Haena; Oh, Hee-Kyun; Kim, Yong-Jun; Kim, Yunpyo; Soum, Veasna; Choi, Jae‐Hak; Kwon, Oh‐Sun; Shin, Kwanwoo

doi:10.1166/jnn.2018.15500

Cited by 5 publications

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“…Low hydrophobicity (contact angle: ~93°) is another drawback of the pre-made LLDPE film; this causes the surface friction to increase, thereby impeding the movement of drops during DMF chip operation. To overcome these limitations, we applied a thin layer of silicone oil on the LLDPE-dielectric film in order to make the surface slippery, thus reducing the surface friction [27,28,29] (Figure 3c). For ease of handling and the avoidance of wrinkles, we used an adhesive plastic frame, to which the LLDPE-dielectric film was fixed to make it flat (Figure 3c).…”

Section: Resultsmentioning

confidence: 99%

Affordable Fabrication of Conductive Electrodes and Dielectric Films for a Paper-Based Digital Microfluidic Chip

et al. 2019

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In order to fabricate a digital microfluidic (DMF) chip, which requires a patterned array of electrodes coated with a dielectric film, we explored two simple methods: Ballpoint pen printing to generate the electrodes, and wrapping of a dielectric plastic film to coat the electrodes. For precise and programmable printing of the patterned electrodes, we used a digital plotter with a ballpoint pen filled with a silver nanoparticle (AgNP) ink. Instead of using conventional material deposition methods, such as chemical vapor deposition, printing, and spin coating, for fabricating the thin dielectric layer, we used a simple method in which we prepared a thin dielectric layer using pre-made linear, low-density polyethylene (LLDPE) plastic (17-μm thick) by simple wrapping. We then sealed it tightly with thin silicone oil layers so that it could be used as a DMF chip. Such a treated dielectric layer showed good electrowetting performance for a sessile drop without contact angle hysteresis under an applied voltage of less than 170 V. By using this straightforward fabrication method, we quickly and affordably fabricated a paper-based DMF chip and demonstrated the digital electrofluidic actuation and manipulation of drops.

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Section: Resultsmentioning

confidence: 99%

Affordable Fabrication of Conductive Electrodes and Dielectric Films for a Paper-Based Digital Microfluidic Chip

et al. 2019

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“…Because most of these dialectic materials are hydrophilic or have low hydrophobicity, for better EWOD performance, a hydrophobic and/or slippery layer is required. Teflon is a common hydrophobic material used for hydrophobic coating while silicon oil is used for generating slippery surfaces [4,69,70]. Summary of some published fabrication methods of p-DMF devices is shown in Table 2.…”

Section: Fabrication Of P-dmf Devicesmentioning

confidence: 99%

Programmable Paper-Based Microfluidic Devices for Biomarker Detections

et al. 2019

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Recent advanced paper-based microfluidic devices provide an alternative technology for the detection of biomarkers by using affordable and portable devices for point-of-care testing (POCT). Programmable paper-based microfluidic devices enable a wide range of biomarker detection with high sensitivity and automation for single- and multi-step assays because they provide better control for manipulating fluid samples. In this review, we examine the advances in programmable microfluidics, i.e., paper-based continuous-flow microfluidic (p-CMF) devices and paper-based digital microfluidic (p-DMF) devices, for biomarker detection. First, we discuss the methods used to fabricate these two types of paper-based microfluidic devices and the strategies for programming fluid delivery and for droplet manipulation. Next, we discuss the use of these programmable paper-based devices for the single- and multi-step detection of biomarkers. Finally, we present the current limitations of paper-based microfluidics for biomarker detection and the outlook for their development.

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Section: Fabrication Of P-dmf Devicesmentioning

confidence: 99%

Micro- and Nanofluidics for Bionanoparticle Analysis

Zeng¹,

Cheng²

2019

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of Surgery at Massachusetts General Hospital. The focus of her research is to develop microfluidic devices for cell and pathogen analysis. In combination with nanomaterials and biosensors, these microfluidic devices are expected to perform automated sample processing and sensitive analyte detection towards point-of-care uses. She has published more than 60 referred technical papers, has been granted several U.S. patents and has obtained research funding from NIH, NSF, and DoD.Yong Zeng currently is a Docking Scholar Associate Professor in the

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Effects of Silicone Oil on Electrowetting to Actuate a Digital Microfluidic Drop on Paper

Cited by 5 publications

References 0 publications

Affordable Fabrication of Conductive Electrodes and Dielectric Films for a Paper-Based Digital Microfluidic Chip

Affordable Fabrication of Conductive Electrodes and Dielectric Films for a Paper-Based Digital Microfluidic Chip

Programmable Paper-Based Microfluidic Devices for Biomarker Detections

Micro- and Nanofluidics for Bionanoparticle Analysis

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