Guiana Dolphin Unusual Mortality Event and Link to Cetacean Morbillivirus, Brazil

Groch, Kátia R.; Santos-Neto, Elitieri; Díaz‐Delgado, Josué; Ikeda, Joana; Carvalho, Rafael R.; Oliveira, Raissa Borges; Guari, Emi B.; Bisi, Tatiana L.; Azevedo, Alexandre F.; Lailson‐Brito, José; Catão‐Dias, José Luiz

doi:10.3201/eid2407.180139

Cited by 52 publications

(76 citation statements)

References 12 publications

(18 reference statements)

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“…PVD caused the death of approximately 18,000 seals (P. vitulina) and hundreds of gray seals (Halichoerus grypus) along the coast of Europe (COSBY et al, 1988). CeMV infection is characterized by histological changes similar to the distemper reported in specimens of P. phocoena stranded on the coast of Ireland and later identified in dead cetaceans on the coast of England, Scotland, and the Netherlands (KENNEDY et al, 1988;GROCH et al, 2018). Since then, several cases of mass mortality have been reported in cetaceans.…”

Section: Natural Impactsmentioning

confidence: 77%

“…In addition, three cases of Morbillivirus were reported in S. guianensis in the state of Paraná and detected by immunohistochemistry (DOMICIANO et al, 2016). However, the discovery of the new GD-CeMV (Guiana dolphin-CeMV) strain specific to S. guianensis was confirmed by compatible molecular and immunohistological analyses, and this strain caused the mass mortality of dolphin populations in Rio de Janeiro (GROCH et al, 2018).…”

Section: Natural Impactsmentioning

confidence: 99%

“…The genus includes different species, whose names refer to the animal from which the virus was isolated, including canine distemper virus (CDV, initially described in canids), rinderpest virus (RPV, in bovids), and phocine distemper virus (PDV, in the seal Phoca vitulina). In cetaceans, cetacean Morbillivirus (CeMV) includes three well-characterized strainsdolphin morbillivirus (DMV, described in the striped dolphin, Stenella coeruleoalba), porpoise morbillivirus (PMV, described in the harbour porpoise, Phocoena phocoena), and pilot whale morbillivirus (PWMV, described in the longfinned pilot whale, Globicephala melas) (HALL, 1995;KENNEDY, 1998)-and three other strains, including the new strain from the Guyana dolphin, Sotalia guianensis (GD-CeMV) (GROCH et al, 2018).…”

Section: Natural Impactsmentioning

confidence: 99%

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Aspectos ambientais e infecciosos relacionados à imunossupressão em cetáceos: uma breve revisão

Koch

Silva

Bracarense

et al. 2018

SCA

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The analysis of the health status of sentinel animals is a key element for the evaluation of ecosystem health conditions, since these animals respond to small and large scale changes in ecological factors and the quality of the environment. In the marine environment, the changes are systemic and accumulate impacts of coastal zones and oceanic activities, with aquatic mammals being species that reflect changes in biological and health parameters. For these animals several studies have reported an increase in the frequency and diversity of diseases, including infections by pathogens from the terrestrial environment. This increase may be related to impairment of the immune system activity of these organisms in response to potential synergistic factors. In cetaceans, immunosuppression may be caused by infection with viral agents, such as Morbillivirus, which induce severe lymphoid depletion and is responsible for several cases of mass mortality; chemical contamination, highlighting the organochlorines and trace elements (mainly mercury and cadmium); and even by chronic stress. Anthropic impacts are important stressors, and the consequences are more evident in animals of coastal habits, which leads to a constant release of glucocorticoid hormones and consequent lymphoid depletion, a mechanism similar to that occurring in terrestrial mammals. Immunosuppressed animals are susceptible to opportunistic diseases, some more severe and rare, with the risk of decline of populations. The objective of this review was to provide information on the aspects related to immunosuppression in cetaceans, associating etiological factors and pathological findings, and to highlight the relevance of the evaluation of the endocrine and immune system of marine animals as a reflection of the health status of marine ecosystems.

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Section: Natural Impactsmentioning

confidence: 77%

Section: Natural Impactsmentioning

confidence: 99%

Section: Natural Impactsmentioning

confidence: 99%

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Aspectos ambientais e infecciosos relacionados à imunossupressão em cetáceos: uma breve revisão

Koch

Silva

Bracarense

et al. 2018

SCA

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“…Recently, another large epizootic of CeMV infection began along the eastern US seaboard which moved southwards in a similar pattern to the 1987 epizootic killing approximately 1650 dolphins from 2013 to 2015 [59,60]. Additionally, CeMV has recently emerged in the Southern Hemisphere as a cause of epizootics among several delphinid species in Australia and Brazil [61][62][63][64][65]. Globally, CeMV infection has now been detected in many species of odontocetes (toothed whales and dolphins) and some mysticetes (baleen whales).…”

Section: Paramyxoviridae: Morbillivirusesmentioning

confidence: 99%

Emerging viruses in marine mammals.

Bossart¹,

Duignan²

2019

CABI Reviews

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Emerging infectious disease has become a serious concern that has consequences for human, animal and environmental health on a global scale. During the past two decades, it has become clear that viruses are emerging in terrestrial environments from the human-animal interface at an unprecedented rate. Thus, the understanding of complex diseases associated with emerging zoonotic pathogens and the creation and execution of strategies to deal with this issue has assumed new public health importance, requiring a One Health approach involving multiple health disciplines. Similar infectious disease trends involving emerging viruses are now being documented in aquatic ecosystems and are impacting marine mammals. As in terrestrial species, emerging viruses in marine mammals may be associated with neoplasia, epizootics and zoonotic disease and involve a complex pathogenesis involving noninfectious cofactors such as anthropogenic toxins, biotoxins, immunologic suppression and other environmental stressors. Among the viruses recently isolated from marine mammals are influenza viruses, morbilliviruses, papillomaviruses, herpesviruses, arboviruses, caliciviruses and others. Many of these emerging marine mammal viruses are associated with disease and specific pathologic findings. In other cases, the disease significance of these novel viruses is unknown and requires further research. In this report, we briefly review emerging viruses that have disease significance for marine mammals and/or public health. Novel concurrent clinicopathologic data will be presented when available broadening the understanding of disease pathogenesis. References will help provide more in-depth information. Additionally, this review has demonstrated that marine mammals may be important sentinel animals that indicate environmental health concerns and parallel emerging public health issues.

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“…Os antibióticos precisam penetrar em quantidades adequadas nos macrófagos e serem estáveis no meio intracelular, para que o tratamento seja eficiente em eliminar a infecção (FUGIER et al, 2007). Usualmente são utilizados dois ou mais antibacterianos associados, os quais envolvem: doxiciclina, ciprofloxacina, trimetropim-sulfa-metoxazol, estreptomicina, gentamicina e rifampicina (PAPPAS et al, 2005;FUGIER et al, 2007 et al, 1988;MCCULLOUGH et al, 1991 (BELLIÈRE et al, 2011;RUBIO-GUERRI et al, 2013;VAN BRESSEM et al, 2014;MAZZARIOL, 2014;STEPHENS et al, 2014;VISSER et al, 1993;BELLIÈRE et al, 2011;RUBIO-GUERRI et al, 2013;DI GUARDO et al, 2011;KEMPER et al, 2016;GROCH et al, 2018). comportamento gregário e a alta densidade de cetáceos podem ocasionar a transmissão horizontal entre os animais (VAN BRESSEM, et al, 1999;HOWLEY, 2001;RAGA et al, 2008;VAN BRESSEM et al, 2014).…”

Section: Bruceloseunclassified

>b<Investigação de infecções por >i<Brucella>/i< e >i<Morbillivirus>/i< em cetáceos e sirênios nas regiões Norte e Nordeste do Brasil>/b<

Sousa¹

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A Deus que sempre esteve ao meu lado e, mesmo diante das dificuldades, me conduziu à realização de mais esse sonho em minha vida. Aos meus pais, José Raimundo Vieira e Jussara Pereira, pelo amor, dedicação, confiança e incentivo em todos os momentos da minha existência. Aos meus irmãos Tatiana Pereira, Angélica Pereira e Thiago Pereira por todo o carinho e conselhos que me deram ao longo desses anos. À Universidade de São Paulo (USP) pela concretização do meu sonho. À Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) pelo auxílio à pesquisa para o desenvolvimento do projeto "Avaliação Sanitária de Sirênios Brasileiros" (processo FAPESP número 2017/19760-6), do qual o presente trabalho é parte. À Profa Dra Lara Keid por ter aceitado me orientar, pela amizade, pelo aprendizado, por ter me ajudado em todas as etapas desse trabalho e pela enorme paciência. Ao Prof Dr Rodrigo Soares pelo apoio em várias situações, pelos ensinamentos e dedicação. À Fernanda Niemeyer e Fábia Luna pelos anos de atividades juntas, pela amizade, incentivo para ingressar no mestrado e apoio nessa jornada. À equipe do Centro Nacional de Pesquisa e Conservação de Mamíferos Aquáticos-ICMBio/CMA pelo apoio e companheirismo. À Acadebio e à Sede do ICMBio (CGGP, Coordenações e DIBIO) por concederem a licença capacitação para finalizar as análises laboratoriais e créditos do mestrado. Às minhas amigas Daniella Ribeiro, Thalita Faita e Jaqueline Diniz pelo carinho, cooperação no laboratório, conselhos, aprendizagem e pelos momentos felizes que estivemos juntas. Às amigas Shara Farias e Vanessa Reis pelo carinho, conselhos e por estarem presentes em grandes momentos da minha estadia em Pirassununga. Aos amigos Alex, Leandro, Marissol e todos do CECSBE pela amizade e apoio durante minha permanência na cidade. Ao Danival Lopes, da Secretaria do VPS/FMVZ a Pós-Graduação pela paciência, dedicação e gentileza. Ao João Metzner do VPS e Ni Devitto pela amizade, apoio e pelos momentos de descontração. Aos servidores, técnicos e tratadores do Centro Nacional de Pesquisa e Conservação da Biodiversidade Marinha do Nordeste-ICMBio/CEPENE em Itamaracá-PE pelo carinho e apoio durante esses anos e pelo envolvimento na conservação dos peixes-bois-marinhos. Aos servidores, técnicos e tratadores do ICMBio/Apa Costa dos Corais em Alagoas por todo o apoio ao longo desses anos e empenho nas questões relacionadas aos peixes-bois-marinhos. À equipe do Centro de Preservação e Pesquisa de Mamíferos Aquáticos (CPPMA) localizado na usina hidrelétrica de Balbina-AM pelo apoio nas coletas, envio de amostras e envolvimento na conservação dos peixes-bois-da-amazônia. Aos veterinários João Carlos Borges e Vanessa Rebelo e a toda a equipe da Fundação Mamíferos Aquáticos (FMA) pela dedicação nas atividades envolvendo os peixes-bois-marinhos, apoio nas coletas e envio de amostras. Aos servidores, técnicos e tratadores do ICMBio/APA Barra de Mamanguape-PB pelo apoio e dedicação aos peixes-bois-marinhos da Paraíba. Aos veterinários Jairo Moura e Ianny Posiadlo, técnicos e t...

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Guiana Dolphin Unusual Mortality Event and Link to Cetacean Morbillivirus, Brazil

Cited by 52 publications

References 12 publications

Aspectos ambientais e infecciosos relacionados à imunossupressão em cetáceos: uma breve revisão

Aspectos ambientais e infecciosos relacionados à imunossupressão em cetáceos: uma breve revisão

Emerging viruses in marine mammals.

>b<Investigação de infecções por >i<Brucella>/i< e >i<Morbillivirus>/i< em cetáceos e sirênios nas regiões Norte e Nordeste do Brasil>/b<

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