The effect of honey consumption compared with sucrose on lipid profile in young healthy subjects (randomized clinical trial)

Hamid, Rizwan; Entezari, Mohammad Hasan; Ghadiri, Ehsan; Mahaki, Behzad; Pahlavani, Naseh

doi:10.1016/j.clnesp.2018.04.016

Cited by 31 publications

(33 citation statements)

References 24 publications

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“…Rasad et al [57] compared the effect of honey consumption and sucrose consumption on lipid profile in young healthy people. One group received 70 g per day of natural honey mixed with 250 mL of tap water.…”

Section: In Vivo Experimentsmentioning

confidence: 99%

“…Both in vitro and animal in vivo experiments have demonstrated that honey can serve as a natural treatment for CVDs through its antioxidant and antiplatelet properties, as well as its other biological potential (Table 2); however, only one experiment has been performed in vivo in a human model, and this was based on a group of young, healthy people. In addition, the study does not define the type of tested honey or its chemical content [57]. Table 2.…”

Section: In Vivo Experimentsmentioning

confidence: 99%

“…Honey (chemical content: undefined) Antioxidant effect (in vitro) [16] Honey (chemical content: undefined) Anti-platelet and anticoagulant effects (in vitro) [48] Medical honey preparations (chemical content: unidentified) Angiogenetic effect (in vitro) [49] Honey (chemical content: undefined) Anti-platelet effect (in vitro) [50] Greek honeys (for example, the total phenolic compounds-5.2 ± 0.2 g GA/kg honey, for fir honey from Karpeniri) Antiatherogenic effect (in vitro) [40] Honey (chemical content: undefined) Antithrombotic effect (mice model) [50] Tualang honey (chemical content: undefined) Antioxidative potential (rat model) [59] Sundarban honey (chemical content: undefined) Antioxidative potential (rat model) [54] Nigerian honey (chemical content: undefined) Modifying lipid metabolism (diabetic rat model) [56] Honey (chemical content: undefined) Modifying lipid metabolism (in young healthy people) [57]…”

Section: Honey Investigated Roles Referencesmentioning

confidence: 99%

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Honey and Its Phenolic Compounds as an Effective Natural Medicine for Cardiovascular Diseases in Humans?

Olas

2020

Nutrients

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Honey is a sweet, viscous syrup produced by the honey bee (Apis mellifera). It is probably the first natural sweetener ever discovered, and is currently used as a nutritious food supplement and medicinal agent. The aim of the present mini-review is to summarize and update the current knowledge regarding the role of honey in CVDs based on various experimental models. It also describes the role of its phenolic compounds in treating CVDs. Many such phenolic and flavonoid compounds, including quercetin, kaempferol, apigenin, and caffeic acid, have antioxidant and anti-platelet potential, and hence may ameliorate cardiovascular diseases (CVDs) through various mechanisms, such as by decreasing oxidative stress and inhibiting blood platelet activation. However, as the phenolic content of a particular type of honey is not always known, it can be difficult to determine whether any observed effects on the human cardiovascular system may be associated with the consumption of honey or its constituents. Therefore, further experiments in this area are needed.

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Section: In Vivo Experimentsmentioning

confidence: 99%

Section: In Vivo Experimentsmentioning

confidence: 99%

Section: Honey Investigated Roles Referencesmentioning

confidence: 99%

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Honey and Its Phenolic Compounds as an Effective Natural Medicine for Cardiovascular Diseases in Humans?

Olas

2020

Nutrients

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“…Abnormal blood lipids, including elevated triglycerides (TG), total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C) and low high density lipoprotein-cholesterol (HDL-C) are independent risk factors for cardiovascular diseases [17][18][19]. Very limited studies have examined the acute [20] and the relatively long-term [12,21] effects of honey consumption on blood lipids in humans. Furthermore, there are limited data regarding whether consumption of honey favorably improves blood lipids, relative to other sweeteners.…”

Section: Introductionmentioning

confidence: 99%

“…A parallel-arm study by Al-Waili et al [13] demonstrated an improvement in the blood lipid profiles of healthy subjects and patients with diabetes and dyslipidemia after consuming honey (1.2 g CHO/kg body weight/day) for only 14 days. Additionally, using a parallel-arm design, Rasad et al [21] demonstrated that honey (70 g/day) can favorably alter blood lipids relative to sucrose in a cohort of young adults (aged 18-30 years). However, more research is needed to determine the short-term and long-term effects of honey consumption on blood lipids and to determine if differences in blood lipid responses vary between honey and sucrose.…”

Section: Introductionmentioning

confidence: 99%

Honey does not adversely impact blood lipids of adult men and women: a randomized cross-over trial

et al. 2020

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Consumption of added sugars in the US is estimated to be approximately 1.5 times recommended levels and has been linked to increased risk for developing chronic diseases. We hypothesized that relative to sugar, honey would reduce energy intake and improve serum lipid profiles. To test this, we assessed the short-term (1-week) and relatively long-term (1-month) effects of honey versus sucrose on changes in dietary intake and serum lipid concentrations. Thirty-seven apparently healthy subjects (21 males; 16 females) aged 24-57 years (BMI = 17.6-37.2 kg/m 2) completed two 4-week trials in a randomized, cross-over design separated by ≥4-week washout. During each trial, subjects consumed either clover honey or sucrose providing 1.2 g/kg/day of carbohydrate under free-living conditions with instructions to avoid changing their habitual food intake. Serum triglyceride (TG) concentrations were elevated (P < .05) after 1 week for both trials but only remained elevated (P < .05) at the 4-week time-point during sucrose consumption. The elevation after 1 week during the honey trial was concurrent with a transient increase (P < .05) in body weight. No effects on serum concentrations of insulin, total cholesterol, low density lipoproteincholesterol, or high density lipoprotein-cholesterol were detected for either trial. Subjects consumed significantly less energy (P < .05), carbohydrate (P < .005), sugars (P < .05), and saturated fat (P < .05) during the honey trial. These data suggest that honey may serve as a favorable substitute for sucrose with regard to reduced energy intake, carbohydrate and sugars, without negatively influencing serum lipid concentrations.

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High versus low-added sugar consumption for the primary prevention of cardiovascular disease

Bergwall

Johansson

Sonestedt

et al. 2022

Cochrane Database of Systematic Reviews

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The effect of honey consumption compared with sucrose on lipid profile in young healthy subjects (randomized clinical trial)

Cited by 31 publications

References 24 publications

Honey and Its Phenolic Compounds as an Effective Natural Medicine for Cardiovascular Diseases in Humans?

Honey and Its Phenolic Compounds as an Effective Natural Medicine for Cardiovascular Diseases in Humans?

Honey does not adversely impact blood lipids of adult men and women: a randomized cross-over trial

High versus low-added sugar consumption for the primary prevention of cardiovascular disease

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