299 Characterisation of Age Related Changes in Left Heart Structure and Function in Young Patients with Ischaemic Stroke

Abstract

glycoprotein-1 antibody consistent with a diagnosis of antiphospholipid syndrome. Given the chronic thromboemboli with associated pulmonary remodelling, riociguat was commenced, later changed to sildenafil in combination with long-term warfarin therapy and she was discharged with excellent recovery. Discussion/Conclusion: We present a rare case of nearfatal acute on chronic sub-massive pulmonary emboli, with successful open clot retrieval to prevent catastrophic paradoxical embolism. Rare cases such as these highlight the importance of multidisciplinary involvement and shared decision-making.