Medical genetics and genomic medicine in Nigeria

Adeyemo, Adebowale; Amodu, Olukemi K.; Ekure, Ekanem N.; Omotade, Olayemi O.

doi:10.1002/mgg3.419

Cited by 15 publications

(27 citation statements)

References 76 publications

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“…Due to the chronic course of sickle cell disease and the unexpected nature of acute and chronic manifestations, patients and their households are generally exposed to a situation that place huge burdens on their finances which may constitute an impediment to care [ 2 , 14 , 15 ]. Hence, this population is particularly in great need of universal health coverage through avenues such as prepayment plans offered in health insurance.…”

Section: Discussionmentioning

confidence: 99%

“…Sickle cell disease is the commonest inherited genetic disorder of haemoglobin in Africa with about 180,000 new births annually of the global 330,000 [ 1 ]. Globally, Nigeria has the highest burden of sickle cell disease occurring in about 2%-3% of new-borns [ 2 ]. It is a chronic disorder characterized by recurrent vaso-occlusive crises requiring frequent hospitalizations.…”

Section: Introductionmentioning

confidence: 99%

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Health insurance and the financial implications of sickle cell disease among parents of affected children attending a tertiary facility in Lagos, south-west Nigeria

Ogamba¹,

Akinsete²,

Mbaso³

et al. 2020

Pan Afr Med J

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Introduction there is a paucity of data on the financial implications of sickle cell disease on households of affected children and their use of health insurance in Nigeria. This study assessed the awareness of health insurance, patterns of health service utilization and financial implications of sickle cell disease among children seeking care at a tertiary facility in Nigeria. Methods a structured questionnaire was administered to parents of 314 children with sickle cell disease attending the pediatric hematology unit of the Lagos University Teaching Hospital between May and December 2019. Results mean age of the children was 91.5 ± 43.1 months. M: F was 1.17: 1. 45.5% of households earned above NGN 150,000 (USD 417) monthly. 71.3% of the parents had heard of health insurance but only 20.7% were enrolled in a health insurance scheme. Awareness of health insurance was significantly associated with social class (p=0.000) and monthly household income (p=0.000). 60.8% of the parents preferred pre-facility treatment. Social class (p=0.01) and monthly household income (p=0.001) were significantly associated with home treatment. Time on admission ranged from 2-18 days with an average of 4.31 days. Average cost of hospitalization was USD 148 ± USD 14.2 and total cost of care incurred was USD 20,787. Neither age of child (p=0.857), estimated household income (p=0.863) nor social class (p=0.397) was associated with cost of care. Conclusion a high cost of care was observed in our study population underscoring the need for increased awareness and access to health insurance for households of children with sickle cell disease.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Health insurance and the financial implications of sickle cell disease among parents of affected children attending a tertiary facility in Lagos, south-west Nigeria

Ogamba¹,

Akinsete²,

Mbaso³

et al. 2020

Pan Afr Med J

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“…In Nigeria, bioinformatics has been nearly two decades old (Fatumo et al, 2014, Adeyemo, et al, 2018, though with lesser national community convening advances in comparison with countries in Eastern and Southern Africa (e.g Kenya and South…”

Section: Justifications For the Conferencementioning

confidence: 99%

First Nigerian Bioinformatics Conference (FNBC): Towards a dynamic bioinformatics community

Ebenezer¹,

Isewon²,

Oladipo³

et al. 2019

Preprint

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The human genome project, which was completed in 2003, ushered in a new era of scientific applications in medicine and bioscience, and also enhanced the generation of high-throughput data which required laboratory and computational analytical approaches in fields known as genomics and bioinformatics respectively. Internationally, specific advances have been achieved which involved the formation and emergence of strong scientific communities to sustain these technological advancements. On the African continent and regionally, the Human Hereditary and Health in Africa (H3Africa), Biosciences eastern and central Africa - International Livestock Research Institute (BecA - ILRI) Hub, and the Alliance for Accelerated Crop Improvements in Africa (ACACIA), are helping to push some of these advances in human health, biosciences, and agriculture respectively. In Nigeria, we believe that significant advances have also been made by various groups since the human genome project was completed. However, a scientific gathering platform to sustainably enable scientists discuss and update these progresses remained elusive. In this article, we report the First Nigerian Bioinformatics Conference (FNBC) hosted by the Nigerian Bioinformatics and Genomics Network (NBGN) in collaboration with the Nigerian Institute of Medical Research (NIMR). The conference was held from 24th - 26th June, 2019, with the theme: “Bioinformatics in the era of genomics in Africa”. Quantitatively, the conference recorded 195 online registered participants, and up to 186 actual participants; comprising of 8 keynote speakers, 6 invited speakers, 25 oral presenters, 83 poster presenters, and up to 73 non-presenting participants. Attendees with national (up to 179) and international (up to 16) affiliations also participated at the conference. Qualitatively, broad scope of bioinformatics, genomics and molecular biology presentations in biomedicine, health, and biosciences were featured at the conference. We discuss the conference structure and activities, lessons learned, and way forward for future bioinformatics conferences in Nigeria. We further discuss the relevance of the conference which presents an increased visibility for the Nigerian bioinformatics community, positions Nigeria as a dynamic community player within the African bioinformatics space, and provides a platform for national impact through the application and implementation of the benefits of bioinformatics.

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“…Bioinformatics and genomics are relatively new scientific disciplines, with surge of interest only in the last two decades. In Nigeria, there has also been considerable engagements by investigators, and the role of Nigeria in these initiatives has previously been reported [8,10]. A metrics for the measurement of this surge of interest could be seen in the increased amount of publications affiliated with Nigerian institutions over the last 5 years (online Supplementary Fig.…”

Section: Introductionmentioning

confidence: 99%

The Nigerian Bioinformatics and Genomics Network (NBGN): a collaborative platform to advance bioinformatics and genomics in Nigeria

Fatumo

Ebenezer

Ekenna

et al. 2020

Glob. Health Epidemiol.

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Africa plays a central importance role in the human origins, and disease susceptibility, agriculture and biodiversity conservation. Nigeria as the most populous and most diverse country in Africa, owing to its 250 ethnic groups and over 500 different native languages is imperative to any global genomic initiative. The newly inaugurated Nigerian Bioinformatics and Genomics Network (NBGN) becomes necessary to facilitate research collaborative activities and foster opportunities for skills’ development amongst Nigerian bioinformatics and genomics investigators. NBGN aims to advance and sustain the fields of genomics and bioinformatics in Nigeria by serving as a vehicle to foster collaboration, provision of new opportunities for interactions between various interdisciplinary subfields of genomics, computational biology and bioinformatics as this will provide opportunities for early career researchers. To provide the foundation for sustainable collaborations, the network organises conferences, workshops, trainings and create opportunities for collaborative research studies and internships, recognise excellence, openly share information and create opportunities for more Nigerians to develop the necessary skills to exceed in genomics and bioinformatics. NBGN currently has attracted more than 650 members around the world. Research collaborations between Nigeria, Africa and the West will grow and all stakeholders, including funding partners, African scientists, researchers across the globe, physicians and patients will be the eventual winners. The exponential membership growth and diversity of research interests of NBGN just within weeks of its establishment and the unanticipated attendance of its activities suggest the significant importance of the network to bioinformatics and genomics research in Nigeria.

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Medical genetics and genomic medicine in Nigeria

Abstract: Medical genetics and genomic medicine in Nigeria.

Cited by 15 publications

References 76 publications

Health insurance and the financial implications of sickle cell disease among parents of affected children attending a tertiary facility in Lagos, south-west Nigeria

Health insurance and the financial implications of sickle cell disease among parents of affected children attending a tertiary facility in Lagos, south-west Nigeria

First Nigerian Bioinformatics Conference (FNBC): Towards a dynamic bioinformatics community

The Nigerian Bioinformatics and Genomics Network (NBGN): a collaborative platform to advance bioinformatics and genomics in Nigeria

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