Measurement of neurovascular coupling in human motor cortex using simultaneous transcranial Doppler and electroencephalography

Alam, Monzurul; Ahmed, Ghazanfar; Ling, Yan To; Zheng, Yongping

doi:10.1088/1361-6579/aac812

Cited by 2 publications

(2 citation statements)

References 28 publications

(31 reference statements)

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“…Previously, there was no simple and effective method for the detection of VBI, but in recent years, with the development and progress of medical technology and the emergence of TCD, it provides an accurate, noninvasive, and simple method for the diagnosis of VBI. Through the diagnosis results, it will be clear about the blood flow status of single vessel, such as diastolic speed, boost index, contraction speed, and vascular compliance, which is helpful for accurate reflection of the subtle changes of VBI [10,11]. In TCD observation index, Vd and Vm are mainly used to reflect the hemodynamic changes of the measured blood vessels, PI, RI, and pulse parameters, and to evaluate the arterial toughness and compliance.…”

Section: Discussionmentioning

confidence: 99%

Evaluation on the application of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency

Zheng

Wang

et al. 2020

J Orthop Surg Res

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Background To evaluate the diagnostic value of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency (VBI) during clinical diagnosis and treatment Methods Eighty patients diagnosed with VBI in our hospital from June 2018 to December 2019 were randomly selected as the observation group, and 80 healthy people who received physical examination in the same period were selected as the control group. The abnormal rate, main performance and results, and the peak velocity of blood flow and vertebrobasilar artery blood flow of the two groups were compared. Results The abnormal rate of EEG and TCD in VBI patients was 38.75% (31/80) and the 93.75% (75/80), respectively. In TCD examination, ACA, PCA, MCA, and VA of both sides of the observation group were higher than those of the control group, while BA was lower than that of the control group (P < 0.05). The Vs, Vd, and Vm on both sides of BA and VA in the observation group were lower than those in the control group, while PI and RI were higher than those in the control group (P < 0.05). Conclusions TCD examination is highly sensitive to the degree and pattern of cerebral ischemia in VBI patients. EEG examination will define the changes of brain cell function after cerebral ischemia. Therefore, EEG and TCD have their own advantages. The application of TCD and EEG can be considered in the early diagnosis, curative effect, and prognosis evaluation of VBI patients, so as to improve the accuracy of diagnosis and prognosis.

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Section: Discussionmentioning

confidence: 99%

Evaluation on the application of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency

Zheng

Wang

et al. 2020

J Orthop Surg Res

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“…[52][53][54][55][56][57] or motor (e.g., finger tapping, arm raises, etc. 58,59 ) tasks are used, as they may not produce a similar response within the MCA. Nevertheless, the present results highlight a foundation future research investigations can build upon to ensure robust and reliable methodological approaches are utilized across the field.…”

Section: Limitationsmentioning

confidence: 99%

Neurovascular coupling on trial: How the number of trials completed impacts the accuracy and precision of temporally derived neurovascular coupling estimates

Burma

Roessel

Oni

et al. 2022

J Cereb Blood Flow Metab

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Standard practices for quantifying neurovascular coupling (NVC) with transcranial Doppler ultrasound (TCD) require participants to complete one-to-ten repetitive trials. However, limited empirical evidence exists regarding how the number of trials completed influences the validity and reliability of temporally derived NVC metrics. Secondary analyses was performed on 60 young healthy participants (30 females/30 males) who completed eight cyclical eyes-closed (20-seconds), eyes-open (40-seconds) NVC trials, using the “Where’s Waldo?” visual paradigm. TCD data was obtained in posterior and middle cerebral arteries (PCA and MCA, respectively). The within-day (n = 11) and between-day ( n = 17) reliability were assessed at seven- and three-time points, respectively. Repeat testing from the reliability aims were also used for the concurrent validity analysis ( n = 160). PCA metrics (i.e., baseline, peak, percent increase, and area-under-the-curve) demonstrated five trials produced excellent intraclass correlation coefficient (ICC) 95% confidence intervals for validity and within-day reliability (>0.900), whereas between-day reliability was good-to-excellent (>0.750). Likewise, 95% confidence intervals for coefficient of variation (CoV) measures ranged from acceptable (<20%) to excellent (<5%) with five-or-more trials. Employing fewer than five trials produced poor/unacceptable ICC and CoV metrics. Future NVC, TCD-based research should therefore have participants complete a minimum of five trials when quantifying the NVC response with TCD via a “ Where’s Waldo?” paradigm.

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Measurement of neurovascular coupling in human motor cortex using simultaneous transcranial Doppler and electroencephalography

Abstract: A combined TCD-EEG system successfully detects ERD and blood flow velocity in cerebral arteries, and can be used as a useful tool to study neurovascular coupling in the brain. There is no significant difference in the hemodynamic responses in healthy young males and females.

Cited by 2 publications

References 28 publications

Evaluation on the application of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency

Evaluation on the application of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency

Neurovascular coupling on trial: How the number of trials completed impacts the accuracy and precision of temporally derived neurovascular coupling estimates

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