Bowel Obstruction and Ventral Hernia After Laparoscopic Versus Open Surgery for Rectal Cancer in A Randomized Trial (COLOR II)

Petersson, Josefin; Koedam, T. W. A.; Bonjer, H. Jaap; Andersson, John; Angenete, Eva; Bock, David; Cuesta, Miguel A.; Deijen, Charlotte L.; Fürst, Alois; Lacy, Antonio M.; Rosenberg, Jacob; Haglind, Eva

doi:10.1097/sla.0000000000002790

Cited by 42 publications

(33 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The aspect of long-term morbidity such as bowel obstruction and incisional and parastomal hernias within 5 years was examined in the COLOR II study, with the conclusion that both open and laparoscopic surgery deliver similar results [38]. The CLASSIC study trial (2005) reported increased positive circumferential resection margins (CRM) for laparoscopic anterior resections in rectal cancer patients compared to the open approach (12.4 vs. 6.3%) [39].…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic and open surgery in rectal cancer patients in Germany: short and long-term results of a large 10-year population-based cohort

et al. 2019

Self Cite

View full text Add to dashboard Cite

Background Rectal cancer is frequent in Germany and worldwide. Several studies have assessed laparoscopic surgery as a treatment option and most have shown favorable results. However, long-term oncologic safety remains a controversial issue. Methods The current dataset derives from 30 clinical cancer registries in Germany and includes 16,378 patients diagnosed with rectal cancer between 2007 and 2016. Outcomes were 90-day mortality, overall survival (OS), local recurrence-free survival (RFS) and relative survival of patients treated with either open or laparoscopic surgery. Multivariable logistic regression was used to evaluate factors that affected the probability of a patient undergoing laparoscopic surgery as well as to evaluate short-term mortality. OS and RFS were analyzed by Kaplan-Meier plots and multivariable Cox regression conducted separately for UICC stages I-III, tumor location, and sex as well as by propensity score matching followed by univariable and multivariable survival analysis. Results Of 16,378 patients, 4540 (27.7%) underwent laparoscopic surgery, a trend which increased during the observation period. Patients undergoing laparoscopy attained better results for 90-day mortality (odds ratio, OR 0.658, 95% confidence interval, CI 0.526-0.822). The 5-year OS rate in the laparoscopic group was 82.6%, vs. 76.6% in the open surgery group, with a hazard ratio (HR) of 0.819 in multivariable Cox regression (95% CI 0.747-0.899, p < 0.001). The laparoscopic group showed a better 5-year RFS, with 81.8 vs. 74.3% and HR 0.770 (95% CI 0.705-0.842, p < 0.001). The 5-year relative survival rates were also in favor of laparoscopy, with 93.1 vs. 88.4% (p = 0.012). Conclusion Laparoscopic surgery for rectal cancer can be performed safely and, according to this study, is associated with an oncological outcome superior to that of the open procedure. Therefore, in the absence of individual contraindications, it should be considered as a standard approach.

show abstract

Section: Discussionmentioning

confidence: 99%

Laparoscopic and open surgery in rectal cancer patients in Germany: short and long-term results of a large 10-year population-based cohort

et al. 2019

Self Cite

View full text Add to dashboard Cite

show abstract

“…Связано это с улучшением восстановления пациентов непосредственно после операции и сопоставимыми отдаленными результатами лечения [1]. С другой стороны, при анализе больших объемов данных было установлено, что нет достоверного различия в частоте образования послеоперационных грыж в 5-летней перспективе у пациентов с лапароскопическими и открытыми резекциями (3,9 %; 95 % доверительный интервал (ДИ) 3,3-4,4 и 4,1 %; 95 % ДИ 3,5-4,6), а при лапароскопическом доступе даже в 2,3 раза повышалась опасность гернио-пластики по экстренным показаниям (отношение рисков (ОР) 2,37; 95 % ДИ 1,03-5,46; p = 0,042) [4,5]. Это подтверждают выводы крупного метаанализа 6 рандомизированных контролируемых и 9 сравнительных исследований (в общей сложности 84 172 пациентов), где в целом после лапароскопической хирургии было меньше шансов на развитие послеоперационной грыжи и спаечной кишечной непроходимости, но при этом потребность в герниопластике либо хирургическом лечении спаечной непроходимости была такая же, как и у пациентов после открытых операций [6].…”

Section: материалы и методыunclassified

The safety of intracorporeal anastomoses after right colectomy during the learning curve

Мельников

Черниковский

Каннер

et al. 2020

Onkol. koloproktol.

View full text Add to dashboard Cite

Objective: to asses safety of installation intracorporeal anastomosis (ICA) in routine practice at learning curve period.Materials and methods. The results of treatment of 102 patients during 2019 were retrospectively analyzed, of which 64 were operated by an expert and 38 passing the ICA learning curve.Results. The operation time was shorter for the expert (145 minutes versus 210 minutes, p <0.05), there was no statistical difference in pathomorphological measurements, the number of lymph nodes removed was oncologically acceptable and did not differ significantly in the two groups. The total number of complications was 25.2 % for all patients, and Clavien–Dindo class IIIB complication rate was also the same (3.2 % vs 2.6 %, p >0.05).Conclusions. The introduction of ICA in right colectomy into routine practice at the stage of passing the learning curve is safe and applicable.

show abstract

“…Несколько чаще ОКН встречается у мужчин (55%) и реже у женщин (45%). В большей степени подвержены риску развития ОКН пожилые люди и лица, которым проведены оперативные вмешательства на кишечнике и желудке [2]. Частота заболеваний острой кишечной непроходимостью относительно невелика и составляет по различным данным от 4 до 20 случаев на 100000 населения.…”

Section: Anesthetized Animals Were Used To Model Different Pathophysiunclassified

Complex Surgical Treatment of Acute Intestinal Obstruction With a Synthetic Peptid Eimpacts Mesenterial and Intestinal Microvasculature

Коваленко¹,

Хугаева²,

Пахомов³

et al. 2018

Zdor. obraz. XXI veke (Ž. naučn. statej)

View full text Add to dashboard Cite

Bowel Obstruction and Ventral Hernia After Laparoscopic Versus Open Surgery for Rectal Cancer in A Randomized Trial (COLOR II)

Abstract: Based on long-term morbidity outcomes, laparoscopic surgery for rectal cancer could be considered a routine technique as there are no differences with open surgery.

Cited by 42 publications

References 24 publications

Laparoscopic and open surgery in rectal cancer patients in Germany: short and long-term results of a large 10-year population-based cohort

Laparoscopic and open surgery in rectal cancer patients in Germany: short and long-term results of a large 10-year population-based cohort

The safety of intracorporeal anastomoses after right colectomy during the learning curve

Complex Surgical Treatment of Acute Intestinal Obstruction With a Synthetic Peptid Eimpacts Mesenterial and Intestinal Microvasculature

Contact Info

Product

Resources

About