Abstract:Veno-venous extracorporeal membrane oxygenation (VV ECMO) is used for support in patients with severe respiratory failure. The method allows extracorporeal gas exchange and may replace the patient's lung function for weeks and even years. ECMO is not a contraindication for lung transplant. The most important factor for a good outcome is the physiological status of the patient when accepted for transplantation. Ambulatory ECMO makes it possible for the patient to exercise and walk, and provides the best outcome… Show more
“…Indeed, ambulatory ECMO, especially for lung transplantation candidates in adult or pediatric populations, is an increasingly frequent practice. 23–25 Early mobilization and physical therapy improve outcomes in critically ill patients. 26…”
Extubation of patients under ECLS is safe and feasible. Furthermore, in extubated patients, we observed fewer cases of ventilator-associated pneumonia and better 30-day survival rates.
“…Indeed, ambulatory ECMO, especially for lung transplantation candidates in adult or pediatric populations, is an increasingly frequent practice. 23–25 Early mobilization and physical therapy improve outcomes in critically ill patients. 26…”
Extubation of patients under ECLS is safe and feasible. Furthermore, in extubated patients, we observed fewer cases of ventilator-associated pneumonia and better 30-day survival rates.
“…Extensive prior cardiothoracic surgical procedures and those requiring lung resection may increase both the technical difficulty of explanting the native lung and the operative risk In the current era, prior cardiothoracic procedures are no longer considered contraindications to lung transplant (43). (53,54).…”
Lung transplant has been established as the treatment of choice for patients with various forms of end-stage lung disease, in whom non-transplant therapeutic options have failed. Many advances in the realms of basic science, clinical research, surgical technique, and perioperative management have emerged over the past few decades; these innovations have contributed to substantial improvements in survival and quality of life for transplant recipients. However, the field of lung transplantation faces appreciable challenges, including expanding the lung donor pool and ameliorating posttransplant complications, such as primary graft dysfunction, cellular-and antibodymediated rejection, chronic lung allograft dysfunction, and infection (1). One of the most important questions
“…2 Further, more prolonged support durations are frequently being used, particularly for respiratory support, where consideration for a cannulation strategy that permits ambulation during ECMO support is paramount. 3 In this issue of the Journal, Orozco-Hernandez and colleagues 4 describe the use of ECMO support in a patient following a bilateral lung transplant complicated initially by right-sided circulatory and respiratory failure with a previous history of right internal jugular vein and superior vena cava thrombosis. Initial cardiopulmonary support was provided with venoarterial ECMO using a 15-French arterial cannula and 21-French multistage venous catheter placed in the right common femoral artery and vein, respectively.…”
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confidence: 99%
“… 2 Further, more prolonged support durations are frequently being used, particularly for respiratory support, where consideration for a cannulation strategy that permits ambulation during ECMO support is paramount. 3 …”
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