The importance of intestinal ultrasound and elastographic techniques in inflammatory bowel diseases

Marin, Andreea Maria; Tribus, Laura; Fierbinţeanu-Braticevici, Carmen

doi:10.11152/mu-1346

Cited by 7 publications

(3 citation statements)

References 93 publications

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“…For instance, it has proven effective in the differentiation of fibrotic from inflammatory strictures in Crohn's disease (14,18) and in assessing and staging rectal tumors (12,13,15). However, there are only a few studies of SWE involving healthy subjects, especially trans-abdominally (20), and the normal elasticity values of the bowel wall measured by SWE remain uncertain (18,(21)(22)(23)(24)(25).…”

Section: Introductionmentioning

confidence: 99%

Using shear wave elasticity in normal terminal ileum of a healthy southwest Chinese population: a pilot study of reference elasticity ranges

Zhao

Gao²,

Zhuang

et al. 2021

Quant Imaging Med Surg

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Background: Elastography has not been widely applied to the gastrointestinal tract. The bowel wall's normal elasticity values are still unknown and are necessary for studies of gastrointestinal diseases. This study explores the feasibility of using shear wave elastography (SWE) to measure the terminal ileum wall stiffness in healthy subjects and establish the corresponding normal ranges of elasticity values.Methods: This observational study recruited 139 healthy adult volunteers from April to July 2020.All examinations were performed in the anterior terminal ileum wall. Shear wave velocity (SWV) and Young's modulus (E) values were measured in the midline on longitudinal sections and replicated different operators' obtained data. Also, bowel wall thickness (BWT) and depth were recorded. Subgroups were classified according to the volunteers' gender, age, body mass index (BMI), BWT, and depth. The intra-class correlation coefficient was calculated to analyze inter-and intra-operator consistency, and independent t-tests and one-way analysis of variance were used to explore the differences in variables. Results:The inter-and intra-operator agreements were good to excellent by different operators and in the replicated measurements (intra-operator consistency: 0.963; inter-operator consistency: 0.842). In all volunteers, the mean SWV was 1.08±0.25 m/s, the mean E value was 3.84±1.84 kPa, and the median BWT was 2 mm. SWV and E did not show significant differences according to gender (P=0.589), age (P=0.738), BMI (P=0.678), depth (P=0.375), or BWT (P=0.410). BWT did not show significant differences according to age (P=0.142), BMI (P=0.863), or depth (P=0.368).Conclusions: SWE can be used in terminal ileum wall stiffness measurements with good reliability, and the SWE values do not appear to vary significantly according to different physiological factors. The corresponding elasticity ranges of the terminal ileum in normal adults were acquired.

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Section: Introductionmentioning

confidence: 99%

Using shear wave elasticity in normal terminal ileum of a healthy southwest Chinese population: a pilot study of reference elasticity ranges

Zhao

Gao²,

Zhuang

et al. 2021

Quant Imaging Med Surg

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“…It was proven that intestinal ultrasound shows increased sensitivity and specificity both in the primary diagnosis of Crohn’s disease and the detection of complications such as stenosis, fistulas, and abscesses [ 22 – 26 ]. The most important marker for inflammation is the thickness of the intestinal wall [ 27 ].…”

Section: Resultsmentioning

confidence: 99%

The role of the intestinal ultrasound in Crohn’s disease diagnosis and monitoring

et al. 2021

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Crohn’s disease is characterized by persistent or recurrent chronic inflammation that may affect any segment of the gastrointestinal tract. It has an oscillating evolution, with periods of activity alternating with periods of remission. Crohn’s disease has a significant impact on the economic status due to its increasing prevalence, often affecting young people. Suitable management for these patients involves frequent evaluations. Even though colonoscopy is the gold standard for the assessment of severity and mucosal healing, it is an invasive maneuver, not easily accepted by patients, and it does not have good repeatability. Intestinal ultrasound has the advantage of being non-irradiating, non-invasive, well-tolerated, cheap, and easy to repeat. Ultrasound parameters such as bowel wall thickness, intestinal wall architecture, intramural vascularisation, proliferation of mesenteric fatty conjunctive tissue, and intraperitoneal fluid can provide good information regarding the severity of the disease, the differentiation between remission and relapse, and its complications. Some of the latest studies show good correlations between ultrasound parameters and inflammation markers (C-reactive protein, fecal calprotectin) and clinical severity scores of Crohn’s disease. Consequently, the importance of intestinal ultrasound has increased lately, and recent studies support its use to evaluate the severity of inflammation, differentiate between active disease and relapse, monitor therapy response and guide treatment, evaluate prognosis, and diagnose complications.

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“…В отечественной и зарубежной литературе появляются сообщения об использовании УЗИ, включая трансабдоминальное УЗИ и ультразвуковую ирригоскопию, для диагностики ВЗК и ПКББ. Чувствительность и специфичность данного метода сопоставимы с соответствующими показателями рентгенологических и эндоскопических методов при ВЗК [33][34][35][36]. УЗИ с использованием допплерографии в энергетическом режиме может применяться как для диагностики локализации воспалительного процесса в толстой и тонкой кишке, так и для оценки активности воспаления не только при ВЗК, но и при ПКББ наряду с эндоскопическим и рентгенологическим методами.…”

Section: капсульная колоноскопияunclassified

Behсet's disease: intestinal damage

Goloeva¹,

Alekberova²

2019

Naučno-praktičeskaâ revmatologiâ

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Behсet's disease (BD) is a systemic vasculitis of an unknown etiology characterized by repeated oral and genital ulcerations and involvement of the eyes, joints, blood vessels, and other organs. In BD, it is the organ pathology that determines the severity and prognosis of the disease. The most difficult and least studied version of such changes is intestinal damage. Its verification in BD is complicated by a variety of clinical manifestations, their similarity with inflammatory bowel diseases, the lack of sufficiently informative laboratory tests, and pathognomonic endoscopic and histological signs. Intestinal BD (IBD) can result in serious complications (severe bleeding, intestinal perforation, and fistula formation), which may not only considerably reduce the quality of life of the patient, but also cause his death. Treatment for IBD is not standardized; it is mainly empirical and is performed as cycles. The goal of its therapy is to achieve clinical remission, to heal intestinal ulcers, to reduce recurrence rates, and to prevent surgery. The cumulative frequency of surgical interventions is as follows: 20% of them are performed in the first year, 27–33% within 5 years, and 31–46% within 10 years after IBD diagnosis. One of the problems in the surgical treatment of patients with IBD is the risk of a recurrence that often requires repeat surgery. Thus, 2- and 5-year postoperative recurrence rates were 29.2 and 47.2%, respectively. The poor prognostic factors are young age (<40 years), high disease activity at the time of diagnosis, detection of crateriform or deep ulcers at colonoscopy, high C-reactive protein level, and history of laparotomy.

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The importance of intestinal ultrasound and elastographic techniques in inflammatory bowel diseases

Cited by 7 publications

References 93 publications

Using shear wave elasticity in normal terminal ileum of a healthy southwest Chinese population: a pilot study of reference elasticity ranges

Using shear wave elasticity in normal terminal ileum of a healthy southwest Chinese population: a pilot study of reference elasticity ranges

The role of the intestinal ultrasound in Crohn’s disease diagnosis and monitoring

Behсet's disease: intestinal damage

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