Fetal overgrowth in pregnancies complicated by diabetes: development of a clinical prediction index

Abstract

This fetal overgrowth index that incorporates five clinical factors provides a means of predicting fetal overgrowth and thereby serves as a tool for targeting the allocation of healthcare resources and treatment individualization.

The Unrealised Potential for Predicting Pregnancy Complications in Women with Gestational Diabetes: A Systematic Review and Critical Appraisal

“…Following title and abstract screening, the full text of 63 articles were assessed. Five studies meeting the selection criteria were included in this review (Figure 1) [21][22][23][24][25].…”

“…The composition of the pregnancy complications predicted varied across the studies. Four studies reported the development of a single prediction model [22][23][24][25]. One study reported the development of six models, one for each of the six outcomes (primary caesarean delivery, birth injury, large-for-gestational-age (LGA), adiposity, hyperinsulinaemia, hypoglycaemia) [21].…”

“…Four prediction modelling studies had a retrospective study design using routinely collected data, three from a single centre [22,23,25] and one from multiple centres [24] (Table 2). One prediction modelling study used a historical cohort from a single centre of a multi-centre prospective observational study [21].…”

“…The study populations varied across studies (Table 3). Two studies included only women with GDM [23,24] while three also included women without GDM [21,22,25]. Diagnostic criteria for GDM varied by region.…”

“…Hence, in this study, 10.5% of participants who would meet the International Association of Diabetes in Pregnancy Study Groups diagnostic criteria for GDM, did not receive any specific treatment for this condition. In the other studies, treatment for GDM followed a standardised institutional protocol [23][24][25] or was not reported [22].…”