“…One of the most striking features of the PV is the intimate proximity of the PVM and PPM, which is maintained until a very late stage of parasite development when PVM rounding occurs just prior to egress (Glushakova et al, 2018;Sherling & van Ooij, 2016). Additional lateral organisation of this compartment is suggested by the formation of distinct oligomeric arrays of EXP1 and ETRAMPs in the PVM (Spielmann, Gardiner, Beck, Trenholme, & Kemp, 2006) and by the nonuniform distribution of PTEX components as well as PV-targeted exported and nonexported fluorescent fusion reporter proteins, which have been shown to display a punctate distribution in the PV described as a "necklace of beads" (Adisa et al, 2003;Bullen et al, 2012;Charnaud, Jonsdottir, et al, 2018;de Koning-Ward et al, 2009;Riglar et al, 2013;Wickham et al, 2001). Visualised by immunofluorescence, this punctate arrangement is most prominent in the early ring stage of parasite development and resolves into a more homogenous distribution in the trophozoite and schizont stage, particularly for EXP2 (Charnaud, Jonsdottir, et al, 2018).…”