Synthesis of highly stable and biocompatible gold nanoparticles for use as a new X-ray contrast agent

Iranpour, Pooya; Ajamian, Maral; Safavi, Afsaneh; Iranpoor, Nasser; Abbaspour, Abdolkarim; Javanmardi, Sanaz

doi:10.1007/s10856-018-6053-5

Cited by 29 publications

(39 citation statements)

References 34 publications

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“…To conclude this section, it is of interest to note that the neutralization reaction for synthesizing ILs has been used with a basic sugar and an acidic reagent by Iranpour et al in 2018 [ 61 ] to obtain the glucosamine-based ionic liquid 65 ( Scheme 14 ). Glucosamine, an amino sugar, is the main constituent of the polysaccharides chitin and chitosan.…”

Section: Synthesismentioning

confidence: 99%

“…Another interesting and popular application of ILs as solvents is their use as reaction media [ 150 , 156 ]: Several papers concerning this topic have been published in the last few years [ 21 , 22 , 23 , 44 , 55 , 56 , 57 , 61 , 103 , 104 , 106 , 107 , 110 ].…”

Section: Applicationsmentioning

confidence: 99%

“…Sugar-derived ILs have been successfully employed as solvent and catalyst/reagent [ 21 , 55 , 56 , 61 , 75 ].…”

Section: Applicationsmentioning

confidence: 99%

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Sugar-Based Ionic Liquids: Multifaceted Challenges and Intriguing Potential

2021

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Carbohydrates represent a promising option in transitioning from oil-based chemical resources to renewable ones, with the goal of developing chemistries for a sustainable future. Cellulose, hemicellulose, and largely available monosaccharides already provide useful chemical building blocks, so-called platform chemicals, such as levulinic acid and hydroxymethyl furfural, as well as solvents like cyrene or gamma-valerolactone. Therefore, there is great anticipation for novel applications involving materials and chemicals derived from sugars. In the field of ionic liquids (ILs), sugar-based ILs have been overlooked for a long time, mainly on account of their multistep demanding preparation. However, exploring new strategies for accessing sugar-based ILs, their study, and their exploitation, are attracting increasing interest. This is due to the growing concerns about the negative (eco)toxicity profile of most ILs in conjunction with their non-sustainable nature. In the present review, a literature survey concerning the development of sugar-based ILs since 2011 is presented. Their preparation strategies and thermal behavior analyses, sorted by sugar type, make up the first two sections with the intention to provide the reader with a useful guide. A final overview of the potential applications of sugar-based ILs and their future perspectives complement the present analysis.

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Section: Synthesismentioning

confidence: 99%

Section: Applicationsmentioning

confidence: 99%

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Sugar-Based Ionic Liquids: Multifaceted Challenges and Intriguing Potential

2021

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“…Besides, Au NPs can be applied for intranasal delivery and then diffused into lymph nodes thus activating CD8+ (T-killer) cell-mediated immune response ( Marques Neto, Kipnis, & Junqueira-Kipnis, 2017 ). Moreover, because of the high atomic number of Au NP, this nanoparticle with high stability and biocompatibility can be utilized as a contrast agent for X-ray based medical imaging, especially in Computed Tomography (CT) ( Iranpour et al, 2018 ).…”

Section: Metal-based Nanoparticlesmentioning

confidence: 99%

Role of different types of nanomaterials against diagnosis, prevention and therapy of COVID-19

Ghaemi

Amiri

Bajuri

et al. 2021

Sustainable Cities and Society

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“…Gold nanoparticles, being an inorganic nanoparticle offer a great advantage in the treatment of COVID-19. Along with gold nanoparticles, various other inorganic nanoparticles like silica nanoparticles, magnetic iron oxide, carbon nanotubes, and quantum dots were assessed as promising transporters of siRNA [72]. Gold NPs were emanated as impressive nanosystems and were evaluated for target-specific gene silencing and as a carrier of siRNA against neoplasm due to their incomparable biocompatibility, adaptable designs, and surface adjustments and thus lead to efficient distribution mechanisms [73].…”

Section: Inorganic Nanoparticlesmentioning

confidence: 99%

State-of-the-Art Nanotechnology Based Drug Delivery Strategies to Combat Covid-19

et al. 2021

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The emerging Coronavirus Disease-19 (COVID-19) pandemic has had a global impact on all important aspects of our society. As it is known, SARS-Cov-2 can withstand up to 72 h in adverse environmental conditions, which can aid its rapid spread. Woefully, an efficacious and approbated vaccine for the SARS-CoV-2 virus remains unavailable, which makes the problem more frightening and presently more complicated bestowing forlorn medical care. Nevertheless, global clinical research is studying several over-the-counter (OTC) drugs approved for other indications to confront coronavirus. Over the past decade, therapeutic nanoparticles have been regarded as a felicitous tool for the efficient and persnickety delivery of therapeutic groups (i.e., drugs, vaccines, siRNAs, and peptides) to the site of infection. They can adequately convey the drug encapsulated nanoparticle to a designated locus without instigating unsought effects. Besides, they acquiesce the use of non-invasive imaging methods to monitor the surface of the infection and the response to treatment. The formulated nanoparticle is apposite for intranasal drug delivery which is a meritorious method to deliver therapeutic moiety for viral diseases affecting the lungs. Applying nanoparticles via intranasal route surmounted several demerits of mucosal administration like circumventing enzymatic degradation of the therapeutic moiety, upgrading and prolonging the action of the drug, etc., and can thus corroborate as an exceptional strategy to encounter respiratory viruses like coronavirus. In this article, we illuminate the promising role of nanoparticles as effective carriers of therapeutic or immunomodulatory agents to help combat COVID-19. The search criteria used were Pubmed, Medscape, Google scholar, etc and the keywords are coronavirus, nanoformulations, nanoparticles, drug delivery, intranasal delivery, etc. The articles range from 2012 to 2020.

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Synthesis of highly stable and biocompatible gold nanoparticles for use as a new X-ray contrast agent

Cited by 29 publications

References 34 publications

Sugar-Based Ionic Liquids: Multifaceted Challenges and Intriguing Potential

Sugar-Based Ionic Liquids: Multifaceted Challenges and Intriguing Potential

Role of different types of nanomaterials against diagnosis, prevention and therapy of COVID-19

State-of-the-Art Nanotechnology Based Drug Delivery Strategies to Combat Covid-19

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