Changes in choroidal thickness following trabeculectomy and its correlation with the decline in intraocular pressure

Silva, Diana; Lopes, Ana Sofia; Henriques, Susana; Lisboa, Maria; Pinto, Soraia; Vaz, Fernando; Prieto, Isabel

doi:10.1007/s10792-018-0918-y

Cited by 4 publications

(2 citation statements)

References 20 publications

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“…In accordance with previous studies performed on trabeculectomy, we found a significant increase in CT both in macula and in peripapillary region after the decline of the IOP, already 24 h after surgery [3,[7][8][9][10].…”

Section: Discussionsupporting

confidence: 92%

Early evaluation of optic nerve head morphology and choroidal thickness after PreserFlo MicroShunt implantation

et al. 2022

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Purpose The aim of this study is to investigate changes in choroidal and optic nerve morphological parameters following MicroShunt PreserFlo implantation. The secondary aim is to investigate how the structural changes relate to the decrease in intraocular pressure (IOP). Methods Prospective observational study on 15 eyes with glaucoma requiring MicroShunt implantation. Optical coherence tomography was used to measure macular choroidal thickness (MCT), peripapillary choroidal thickness (PCT), lamina cribrosa depth (LCD), cup depth and prelaminar tissue thickness (PLT), before and one day after surgery. Results were expressed in median and interquartile range (IQR) and correlated with IOP results. Results The IOP decreased from a median of 25 (IQR = 11) mmHg to 8 (IQR = 2) mmHg the day after surgery. Median MCT increased after MicroShunt implantation from 252.1 (IQR = 156.4) µm to a postoperative value of 318.1 (IQR = 166.6) µm (p < 0.001), with a median increase of + 87.7 µm (+ 26.4%). PCT increased from 157.2 (IQR = 109.1) µm before surgery to 206.0 (IQR = 136.1) µm after surgery (p < 0.001). Moreover, we found a significant post-operative decrease in cup depth (median reduction of − 29.3 µm, p < 0.001) and an increase in PLT (median increase of 27.3 µm, p = 0.028). On the other side, LCD reduction 24 h after surgery didn’t reach any statistical significance. Conclusion PreserFlo implantation determines retinal structural changes which appear similar to those caused by traditional filtering surgery, confirming the effectiveness of this device, meantime carrying a much smaller complications rate when compared to trabeculectomy.

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Section: Discussionsupporting

confidence: 92%

Early evaluation of optic nerve head morphology and choroidal thickness after PreserFlo MicroShunt implantation

et al. 2022

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“…In the literature, SFCT tends to be negatively correlated to IOP [ 33 , 34 , 35 , 36 , 37 , 38 ]. As both IOP and SFCT decrease in our study, IOP variation does not explain the SFCT decreases.…”

Section: Discussionmentioning

confidence: 99%

Effect of SCUBA Diving on Ophthalmic Parameters

et al. 2022

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Background and Objective: Several cases of central serous chorioretinopathy (CSC) in divers have been reported in our medical retina center over the past few years. This study was designed to evaluate possible changes induced by SCUBA diving in ophthalmic parameters and especially subfoveal choroidal thickness (SFCT), since the choroid seems to play a crucial role in physiopathology of CSC. Materials and Methods: Intraocular pressure (IOP), SFCT, pachymetry, flow-mediated dilation (FMD), blood pressure, and heart rate were measured in 15 healthy volunteer divers before diving, 30 and 60 min after a standard deep dive of 25 m depth for 25 min in a dedicated diving pool (NEMO 33). Results: SFCT reduces significantly to 96.63 ± 13.89% of pre-dive values (p = 0.016) 30 min after diving. It recovers after 60 min reaching control values. IOP decreases to 88.05 ± 10.04% of pre-dive value at 30 min, then increases to 91.42 ± 10.35% of its pre-dive value (both p < 0.0001). Pachymetry shows a slight variation, but is significantly increased to 101.63 ± 1.01% (p = 0.0159) of the pre-dive value, and returns to control level after 60 min. FMD pre-dive was 107 ± 6.7% (p < 0.0001), but post-dive showed a diminished increase to 103 ± 6.5% (p = 0.0132). The pre-post difference was significant (p = 0.03). Conclusion: Endothelial dysfunction leading to arterial stiffness after diving may explain the reduced SFCT observed, but SCUBA diving seems to have miscellaneous consequences on eye parameters. Despite this clear influence on SFCT, no clear relationship between CSC and SCUBA diving can be drawn.

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Changes in Macular Thickness after Cataract Surgery in Patients with Open Angle Glaucoma

et al. 2023

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Background: The purpose of this study was to examine the changes in IOP, total macular and RNFL, ganglion cell layer (GCL) thickness, and aqueous humour flare in open angle glaucoma (OAG) patients before and 6 months after cataract surgery. Methods: This was a prospective observational case–control age- and gender-matched study. Groups: 40 subjects in a controlled OAG (OAGc) group, 20 subjects in an uncontrolled OAG (OAGu) group, and 60 control group subjects. Examination: complete ophthalmic evaluation, IOP measurement, anterior and posterior segment Optical Coherence Tomography (OCT), and laser flare photometry before and 6 months postoperatively. Results: Six months postoperatively IOP decreased in all groups. An increase in macular thickness was found postoperatively in all groups. Preoperative aqueous humour flare was higher in the OAGc group than in the control group. After cataract surgery, aqueous humour flare was higher in the control group compared to the preoperative result. Conclusions: Changes in IOP following cataract surgery were strongly negatively correlated with preoperative IOP. An increase in macular thickness was observed 6 months postoperatively in all groups. Aqueous humour flare did not differ in OAGc and OAGu groups pre- and postoperatively but significantly increased in the control group postoperatively.

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Changes in choroidal thickness following trabeculectomy and its correlation with the decline in intraocular pressure

Abstract: Choroidal thickness appears to increase temporarily after trabeculectomy and these changes were not correlated with the decline in intraocular pressure. Further research is required to fully understand this phenomenon.

Cited by 4 publications

References 20 publications

Early evaluation of optic nerve head morphology and choroidal thickness after PreserFlo MicroShunt implantation

Early evaluation of optic nerve head morphology and choroidal thickness after PreserFlo MicroShunt implantation

Effect of SCUBA Diving on Ophthalmic Parameters

Changes in Macular Thickness after Cataract Surgery in Patients with Open Angle Glaucoma

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