The Impact of Groin Surgery during Childhood on the Incidence of Inguinal Hernia Repair and Its Postoperative Complications in Adult Life

Sokratous, Arestis; Österberg, Johanna; Sandblom, Gabriel

doi:10.1055/s-0038-1641598

Cited by 5 publications

(2 citation statements)

References 18 publications

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“…We do not have any information about previous IH as a child; a previous study identified a slightly increased risk of IH formation later in life if a male has undergone IH repair in childhood (Sokratous et al, 2019). This increase is so small that we believe that the large cohort will cover for this.…”

Section: Discussionmentioning

confidence: 99%

Androgen Deprivation Therapy and the Risk for Inguinal Hernia: An Observational Nested Case Control Study

et al. 2021

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It has been suggested that hypogonadism increases the risk for inguinal hernia (IH). The aim of this study was to investigate any association between androgen deprivation therapy (ADT) for prostate cancer and increased risk for IH. The study population in this population-based nested case-control study was based on data from the Prostate Cancer Database Sweden. The cohort included all men with prostate cancer who had not received curative treatment. Men who had been diagnosed or had undergone IH repair ( n = 1,324) were cases and controls, where not diagnosed, nor operated on for IH, matched only on birth year ( n = 13,240). Conditional multivariate logistic regression models were used to assess any temporal association between ADT and IH, adjusting for marital status, education level, prostate cancer risk category, Charlson Comorbidity Index, ADT, time since prostate cancer diagnosis, and primary prostate cancer treatment. Odds ratio (OR) for diagnosis/repair of IH 0 to 1 year from start of ADT was 0.5 (95% confidence interval [CI] = [0.38, 0.68]); between 1 and 3 years after, the OR was 0.35 (95% CI = [0.26, 0.47]); between 3 and 5 years after, the OR was 0.39 (95% CI = [0.26, 0.56]); between 5 and 7 years after, the OR was 0.6 (95% CI = [0.41, 0.97]); and >9 years after, the OR was 3.68 (95% CI = [2.45, 5.53]). The marked increase in OR for IH after 9 years of ADT supports the hypothesis that low testosterone levels increase the risk for IH. The low risk for IH during the first 8 years on ADT is likely caused by selection of men with advanced cancer unlikely to be diagnosed or treated for IH.

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Section: Discussionmentioning

confidence: 99%

Androgen Deprivation Therapy and the Risk for Inguinal Hernia: An Observational Nested Case Control Study

et al. 2021

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“…However, nationwide data have been scarcely presented for paediatric inguinal hernias and were largely restricted to Denmark [ 2 ], Taiwan [ 3 ], and England [ 4 ] based on their large health insurance-based registries. The Swedish registry data has so far only been used to investigate specific narrow research questions in adolescents [ 5 ], as has a large insurance database in Japan [ 6 ]. Contrary to this situation in paediatric inguinal hernia repair, research in adults may not only rely on large-scale registries from different countries [ 7 ], but also on routine administrative data [ 8 ] and even the combination of both [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Inguinal hernia repair in inpatient children: a nationwide analysis of German administrative data

et al. 2021

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Background Contrary to adult inguinal hernia surgery, large-scale investigations using registries or administrative data are missing in paediatric surgery. We aimed to fill this gap by analysing German administrative hospital data to describe the current reality of inpatient hernia surgery in children. Methods We analysed aggregated data files bought from the German federals statistics office on hospital reimbursement data separately for principal diagnoses of inguinal hernia in children and for herniotomies in inpatients. Developments over time were assessed via regression and differences between groups with nonparametric comparisons. Results Principal diagnoses of hernias were decreasing over time with the exception of male bilateral and female bilateral incarcerated hernias in the first year of life which increased. The vast majority of operations were conducted via the open approach and laparoscopy was increasingly only used for females older than 1 year of age. Recurrent hernia repair was scarce. Rates of inguinal hernia repair were higher in both sexes the younger the patient was, but were also decreasing in all age groups despite a population growth since 2012. The amount of inguinal hernia repairs by paediatric surgeons compared to adult surgeons increased by 1.5% per year. Conclusions Our results corroborate previous findings of age and sex distribution. It demonstrates that inpatient hernia repair is primarily open surgery with herniorrhaphy and that recurrences seem to be rare. We observed decreasing rates of hernia repairs over time and as this has been described before in England, future studies should try to elucidate this development. Level of evidence III.

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The efficacy and safety of preoperative glucocorticoids in herniorrhaphy: a systematic review and meta-analysis

et al. 2022

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The Impact of Groin Surgery during Childhood on the Incidence of Inguinal Hernia Repair and Its Postoperative Complications in Adult Life

Abstract: Individuals undergoing surgery in the groin during childhood are at increased risk for acquired inguinal hernia surgery later in life. Inguinal surgery during childhood did not affect the outcome of hernia repair in adult age.

Cited by 5 publications

References 18 publications

Androgen Deprivation Therapy and the Risk for Inguinal Hernia: An Observational Nested Case Control Study

Androgen Deprivation Therapy and the Risk for Inguinal Hernia: An Observational Nested Case Control Study

Inguinal hernia repair in inpatient children: a nationwide analysis of German administrative data

The efficacy and safety of preoperative glucocorticoids in herniorrhaphy: a systematic review and meta-analysis

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