Double venous compression due to duplicated inferior vena cava-induced right common iliac vein thrombosis

Abstract

Venous compression syndromes are caused by extrinsic venous compression of anatomical structures, such as the adjacent arteries and bones. Chronic venous compression and pulsative vibratory arterial pressure accelerate the development of deep vein thrombosis. Herein, we report the first case of double venous compressions due to a duplicated inferior vena cava-induced right-sided common iliac vein thrombosis. The thrombus was induced by left-sided inferior vena cava entrapment and right-sided common iliac vein compression, resembling nutcracker syndrome and May-Thurner syndrome, respectively. Bypass flow of the right inferior vena cava rendered the right lower extremity asymptomatic. Once daily anticoagulation edoxaban was effective. Congenital venous anomalies and bypass formations should be considered when a common iliac vein thrombus without symptoms in the lower extremities is observed, and a lifelong periodical follow-up is mandatory, even after remission.

A case of duplicated inferior vena cava with bilateral iliac vein compression

“…A previous paper by Mukai et al found that double venous compression due to a duplicated inferior vena cava can induce right-sided common iliac vein thrombosis. 4 Here, double venous compression caused by a duplicated IVC rendered the venous flow stasis more complicated. The case is unique, as our patient was a male in his late 80s and had significant compression of the bilateral iliac veins.…”

Duplication of the inferior vena cava: a case series

“…This inadequate blood return may increase the blood pressure in the veins of the lower extremities, resulting in venous stasis and subsequent DVT. 8 For young patients with DVT of the lower extremities, we must be alert to IVC anomalies including duplication of the IVC. Among our five patients, three had no thrombosis event and were incidentally diagnosed by imaging.…”