296 Shoulder laxity and impingement in elite swimmers

Sein, Mya Lay; Walton, Julia; Linklater, James; Appleyard, Richard; Kirkbride, Brent; Kuah, Donald; Murrell, G.

doi:10.1016/s1440-2440(17)30793-4

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is debate as to whether a loss of integrity of the matrix, or the cells in the tendon matrix, initiate the changes in tendinopathy. Given the high incidence about (70%) of tendinopathy in the shoulders of ''elite'' asymptomatic swimmers [98] we favor the later. High doses of cyclical strain induce genes for two major pathways ( Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Excessive long-distance running, intensity, and hill work are risk factors for acute Achilles tendinopathy [60,70,95]; distance and excessive time spent swimming are associated with supraspinatus tendinopathy [98]. There is also an association between tendinopathy and hormone replacement therapy and oral contraceptives in women [47].…”

Section: Common Intrinsic and Extrinsic Associationsmentioning

confidence: 99%

See 1 more Smart Citation

The Basic Science of Tendinopathy

Murrell

2008

Clinical Orthopaedics &Amp; Related Research

309

254

View full text Add to dashboard Cite

Tendinopathy is a common clinical problem with athletes and in many occupational settings. Tendinopathy can occur in any tendon, often near its insertion or enthesis where there is an area of stress concentration, and is directly related to the volume of repetitive load to which the tendon is exposed. Recent studies indicate tendinopathy is more likely to occur in situations that increase the ''dose'' of load to the tendon enthesis -including increased activity, weight, advancing age, and genetic factors. The cells in tendinopathic tendon are rounder, more numerous, and show evidence of oxidative damage and more apoptosis. These cells also produce a matrix that is thicker and weaker with more water, more immature and cartilage-like matrix proteins, and less organization. There is now evidence of a population of regenerating stem cells within tendon. These studies suggest prevention of tendinopathy should be directed at reducing the volume of repetitive loads to below that which induces oxidative-induced apoptosis and cartilage-like genes. The management strategies might involve agents or cells that induce tendon stem cell proliferation, repair and restoration of matrix integrity.

show abstract

Section: Discussionmentioning

confidence: 99%