The effects of prebiotic supplementation on weight gain, diarrhoea, constipation, fever and respiratory tract infections in the first year of life

Shahramian, Iraj; Kalvandi, Gholamreza; Javaherizadeh, Hazhir; Khalili, Manijeh; Noori, Noor Mohammad; Delaramnasab, Mojtaba; Bazi, Ali

doi:10.1111/jpc.13906

Cited by 36 publications

(32 citation statements)

References 33 publications

(59 reference statements)

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“…For prebiotics, the use of fructans and glucans in infant formulae resulted in fewer (P < 0.01) episodes of physician-diagnosed overall and upper respiratory tract infections (n=66) compared to controls without prebiotics (n=68) (45) . In another trial, Shahramian et al (50) used galactans and polydextose to reduce respiratory tract infections in formula fed infants (n=60) studied over one year (p=0.01, compared to controls without prebiotics n=60). Effects were comparable to those of breast fed infants (n=60).…”

Section: Aspects Of Gut Microbiota Modulation Related To Respiratory mentioning

confidence: 99%

Mechanisms linking the human gut microbiome to prophylactic and treatment strategies for COVID-19

2020

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The recent COVID-19 pandemic has altered the face of biology, social interaction and public health worldwide. It has had a destructive effect upon millions of people and is approaching a devastating one million fatalities. Emerging evidence has suggested a link between the infection and gut microbiome status. This is one of several factors that may contribute towards severity of infection. Given the fact that the gut is heavily linked to immunity, inflammatory status and the ability to challenge pathogens, it is worthwhile to consider dietary intervention of the gut microbiota as means of potentially challenging the viral outcome. In this context, probiotics and prebiotics have been used to mitigate similar respiratory infections. Here, we summarise links between the gut microbiome and COVID-19 infection, as well as propose mechanisms whereby probiotic and prebiotic interventions may act.

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Section: Aspects Of Gut Microbiota Modulation Related To Respiratory mentioning

confidence: 99%

Mechanisms linking the human gut microbiome to prophylactic and treatment strategies for COVID-19

2020

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“…There is evidence to support the effectiveness of using prebiotics in viral diseases, including respiratory diseases, although most studies have been conducted with individuals in their infancy (99)(100)(101) . In this sense, associations between the effects of prebiotic consumption on the gut microbiota and immunity-related to respiratory infections, especially on COVID-19 symptoms, constitute a challenge to be investigated (56) .…”

Section: The Role Of Prebiotics In the Immune System And Respiratory Infectionsmentioning

confidence: 99%

Probiotics and prebiotics: potential prevention and therapeutic target for nutritional management of COVID-19?

et al. 2021

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Scientists are working to identify prevention/treatment methods and clinical outcomes of Coronavirus Disease 2019 (COVID-19). Nutritional status and diet have a major impact on the COVID-19 health-disease process, mainly due to the bidirectional interaction between gut-lung axis. Individuals with inadequate nutritional status have a pre-existing imbalance in the gut microbiota and immunity as seen in obesity, diabetes, hypertension, or other chronic diseases. Communication between the gut microbiota and lungs or other organs and systems may trigger worse clinical outcomes in viral respiratory infections. Thus, this review addresses new insights into the use of probiotics and prebiotics as a preventive nutritional strategy in managing respiratory infections such as COVID-19 and highlighting their anti-inflammatory effects against the main signs and symptoms associated with COVID-19. The search for studies was performed through Pubmed, Cochrane Library, Scopus, and Web of Science databases; relevant clinical articles were included. Significant randomized clinical trials suggest that specific probiotics and/or prebiotics reduce diarrhoea, abdominal pain, vomiting, headache, cough, sore throat, fever, and viral infection complications such as acute respiratory distress syndrome. These beneficial effects are linked with modulation of the microbiota, products of microbial metabolism with antiviral activity, and immune regulatory properties of specific probiotics and prebiotics through of Treg cell production and function. There is a need to conduct clinical and pre-clinical trials to assess the effect of consuming these components together with the current therapies in COVID-19.

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“…It is important to pay attention to infectious diseases in children (18). One of the emerging diseases that has spread in 2019 is COVID-19 (19,20).…”

Section: Contextmentioning

confidence: 99%

Laboratory and Radiologic Findings in Pediatrics with COVID-19: A Systematic Review

Shokri

Karimian

Mansouri

et al. 2020

Arch Clin Infect Dis

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Context: One of the emerging diseases that has spread in 2019 is COVID-19. Objectives: The present systematic review (SR) was performed to evaluate the status of laboratory and radiological findings in the age group of children and adolescents with COVID-19. Methods: In this SR study, three of the research team members conducted searches in SCOPUS, PUBMED, Science Direct, and ISI international sites. The keywords that were searched included children- pediatric- adolescents- coronavirus- COVID-19- Novel coronavirus SARS-CoV-2-epidemiology- diagnostic findings- laboratory findings- CT SCAN- computed tomography- percentage of lymphocyte- alanine aminotransferase- white blood cell count (WBC). The combination of search keywords with AND as well as OR was performed. For analysis, descriptive data reporting was performed using EndNote software. Results: The analysis of the laboratory and radiology findings of 197 patients of 12 studies included in the SR study showed notable changes in the lung CT scan and laboratory ranges that confirm the COVID-19 infection in these patients. Conclusions: This systematic review provides information on the laboratory and radiology findings of children and adolescents with COVID-19 for the health care team.

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The effects of prebiotic supplementation on weight gain, diarrhoea, constipation, fever and respiratory tract infections in the first year of life

Cited by 36 publications

References 33 publications

Mechanisms linking the human gut microbiome to prophylactic and treatment strategies for COVID-19

Mechanisms linking the human gut microbiome to prophylactic and treatment strategies for COVID-19

Probiotics and prebiotics: potential prevention and therapeutic target for nutritional management of COVID-19?

Laboratory and Radiologic Findings in Pediatrics with COVID-19: A Systematic Review

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