Postmortem interval estimation using the animal model of postmortem gas volume changes

Iwamoto, Chika; Ohuchida, Kenoki; Okumura, Miki; Usumoto, Yosuke; Kishimoto, Junji; Murata, Masaru; Ikeda, Noriaki; Hashizume, Makoto

doi:10.1016/j.legalmed.2017.12.010

Cited by 10 publications

(2 citation statements)

References 12 publications

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“…of post-mortem period. However, in contrast to our study, they did not examine the effects of environmental factors (24). In addition to our findings, the literature shows that the organs' minor structural decomposition due to enzymatic autolysis or bacterial decay results in changes in the CT attenuation values, which might be used in the estimation of early PMI.…”

Section: Discussioncontrasting

confidence: 85%

Post-Mortem Interval Estimation Based on Liver and Striated Muscle Computed Tomography Attenuations in Rats

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et al. 2023

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OBJECTIVE: The interest on post-mortem computed tomographic studies targeting post-mortem interval (PMI) estimations is increasing. Most studies have been conducted in an uncontrolled or relatively less controlled condition. However, this study investigates the usefulness of computed tomography attenuations of the liver and striated muscles in PMI estimation under strictly controlled environmental conditions. MATERIAL AND METHODS: Post-mortem computed tomography images of 30 Wistar Albino rats were obtained in the first 30 min after death and 12, 24, 36, 48, 72, 96, 120, 144 and 168-hours following death. Repeated attenuations of both thelateral lobes of the liver and paraspinal muscle were recorded in 0.12-cm2 regions of interest. RESULTS: The attenuation values of the liver and paraspinal muscles were higher 12-hour post-mortem. A significant difference was observed between the images obtained 30 minutes post-mortem and those obtained 12 hours post-mortem in both male (p=0.01) and female rats (p=0.01). Different cut-off attenuation values for the liver and muscle tissue were determined to estimate the post-mortem interval. CONCLUSIONS: The use of attenuation values of the liver and striated muscles with the proposed model was found to be beneficial for the determination of PMI. The cut-off values of attenuation, especially for the liver, can be used in the delimitation of the post-mortem interval.

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Section: Discussioncontrasting

confidence: 85%

Post-Mortem Interval Estimation Based on Liver and Striated Muscle Computed Tomography Attenuations in Rats

Yıldırım

Tümer

Akçan

et al. 2023

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“…For example, fluid shifts in the chest mean that volume of pleural effusion and the amount of restricted diffusion in different organs could be informative, but as yet none of these have proven to be robust markers to support routine measurement. While the total volume of gas within the body alters with PMI and can be detected with PMCT, this work has so far focused on animal and adult studies with variable results …”

Section: Introductionmentioning

confidence: 99%

Latest developments in post‐mortem foetal imaging

et al. 2019

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A sustained decline in parental consent rates for perinatal autopsies has driven the development of less‐invasive methods for death investigation. A wide variety of imaging modalities have been developed for this purpose and include post‐mortem whole body magnetic resonance imaging (MRI), ultrasound, computed tomography (CT) and micro‐focus CT techniques. These are also vital for “minimally invasive” methods, which include potential for tissue sampling, such as image guidance for targeted biopsies and laparoscopic‐assisted techniques. In this article, we address the range of imaging techniques currently in clinical practice and those under development. Significant advances in high‐field MRI and micro‐focus CT imaging show particular promise for smaller and earlier gestation foetuses. We also review how MRI biomarkers such as diffusion‐weighted imaging and organ volumetric analysis may aid diagnosis and image interpretation in the absence of autopsy data. Three‐dimensional printing and augmented reality may help make imaging findings more accessible to parents, colleagues and trainees.

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Predictive equation for post-mortem interval using spectrophotometric values of post-mortem lividity: A pilot study

Usumoto

Kudo

Tsuji

et al. 2019

Forensic Science International

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Postmortem interval estimation using the animal model of postmortem gas volume changes

Cited by 10 publications

References 12 publications

Post-Mortem Interval Estimation Based on Liver and Striated Muscle Computed Tomography Attenuations in Rats

Post-Mortem Interval Estimation Based on Liver and Striated Muscle Computed Tomography Attenuations in Rats

Latest developments in post‐mortem foetal imaging

Predictive equation for post-mortem interval using spectrophotometric values of post-mortem lividity: A pilot study

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