“…Furthermore, ezrin deletion in autophagic TAMs decreased TGF-β1 expression and contributed to EMT as well as the cell migration and invasion ability of lung adenocarcinomas. Ezrin, an important regulatory protein that connects cell membrane molecules, is highly expressed in various solid tumors and is associated with poor prognosis (35,36). Chen et al reported that ezrin can mediate EMT in A549 cells through the TGF-β1 pathway (37).…”