Splenic Rupture in Children With Portal Hypertension

Waisbourd‐Zinman, Orith; Shah, Ankur; Lin, Henry C.; Rand, Elizabeth B.

doi:10.1097/mpg.0000000000001800

Cited by 4 publications

(1 citation statement)

References 3 publications

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“…[ 10 ] In addition, in the early stage of splenectomy patients, the platelet count and the blood viscosity was significantly increased. [ 11 ] On the one hand, the blood supply decreased at the same time, resulting in insufficient blood supply to myocardial cells, resulting in myocardial damage, and a large amount of myocardial enzymes being released into the blood. it increases the risk of vascular embolism, leading to an increased possibility of vascular-related complications such as myocardial infarction.…”

Section: Discussionmentioning

confidence: 99%

Changes to the myocardial enzyme spectrum in patients with different degrees of spleen injury and their clinical value

Han

Zheng-wu

et al. 2022

Medicine

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To investigate the changes to the myocardial enzyme profile and its clinical value in patients with different degrees of spleen injury. Of all patients who underwent total splenectomy due to trauma-induced spleen injury from January 2019 to January 2022 were selected, 70 patients with grade III and IV spleen injuries were selected as the experimental group. In addition, 70 patients with grade I and II were selected as control group 1, and another 70 patients as control group 2. The levels of creatine kinase (CK), creatine kinase isoenzyme (CK-MB), lactate dehydrogenase (LDH) in the 3 groups were detected before (T0) and on the 1st day (T1) after surgery, on the 3rd day (T2) and on the 7th day (T3) after surgery, and on the 14th day (T4) after surgery, respectively, to analyze the relationship with the severity of spleen injury. The spleen injury experimental group, control group 1, and control group 2 were all cured and discharged after corresponding treatment, and there was no myocardial infarction within 3 months of hospitalization and discharge follow-up. The experimental group had higher CK, CK-MB, and LDH than control group 1 and control group 2 at the same time point from T0 to T4 (P<.05); the CK and CK-MB of control group 1 were higher than those of control group 2 at the same time points from T0 to T4 (P < .05), the LDH at points T0 to T2 was higher than that of control group 2 (P < .05), and the LDH was lower at points T3 and T4. Compared with T0 in the same group, CK, CK-MB, and LDH at T1 to T4 in the 3 groups were all lower than those at T0 (P < .05). The early peripheral blood myocardial enzyme spectrum of patients with different degrees of spleen injury is increased, and the increase of myocardial enzyme spectrum is positively correlated with the severity of spleen injury, suggesting that patients with traumatic spleen injury may have myocardial damage in the early stage, and should be treated as soon as possible.

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Section: Discussionmentioning

confidence: 99%