Cavernous Transformation and Granulomatous Epididymis in Behçet Disease

Abstract

Superficial vein thrombosis of the extremities and thrombosis of the deep veins of the lower extremities are common in BD; however, the formation of cavernous portal vein is rare. A 47year-old man had been diagnosed with granulomatous epididymitis when he was 30 years old. He developed uveitis 4 years later and was treated with glucocorticoids based on a diagnosis of suspected sarcoidosis. Computed tomography performed when he was 40 years old revealed a cavernous transformation of the portal vein, but the etiology remained unknown. In January 2017, he experienced a relapse of the uveitis with high fever, and erythema nodosum and genital ulcerations developed. Human leukocyte antigen B51 was detected. Finally, he was diagnosed with Behçet's disease (BD), and vascular involvement was suspected. After admission to our hospital, his fever spontaneously resolved and treatment with colchicine was initiated to prevent relapse. Portal vein involvement is very rare in BD, and the presence of a granuloma might delay the diagnosis of BD.