Protective Effect of a Novel Technique for Liver Transplantation in the Rat

Qu, Biao; Yu, Fei; Sheng, Guoqing; Zhang, W.; Zhang, Y.-M.; Deng, Ying; Shi, Yuan; Shen, Zhongyang

doi:10.1016/j.transproceed.2017.12.020

Cited by 2 publications

(1 citation statement)

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“…This technique consists of attaching the magnetic rings to the donor’s and recipient’s SHVC. 83 However, there are some limitations to this technique, such as a short SHVC of some rats and magnetic rings interfering with the scan during magnetic resonance image evaluation. Furthermore, other steps such as the re-arterialization must be performed to improve this novel model for OLT studies.…”

Section: Liver Transplantationmentioning

confidence: 99%

Liver scaffolds obtained by decellularization: A transplant perspective in liver bioengineering

2022

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Liver transplantation is the only definitive treatment for many diseases that affect this organ, however, its quantity and viability are reduced. The study of liver scaffolds based on an extracellular matrix is a tissue bioengineering strategy with great application in regenerative medicine. Collectively, recent studies suggest that liver scaffold transplantation may assist in reestablishing hepatic function in preclinical diseased animals, which represents a great potential for application as a treatment for patients with liver disease in the future. This review focuses on useful strategies to promote liver scaffold transplantation and the main open questions about this context. We outline the current knowledge about ex vivo bioengineered liver transplantation, including the surgical techniques, recipient survival time, scaffold preparation before transplantation, and liver disease models. We also highlight the current limitations and future directions regarding in vivo bioengineering techniques.

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Section: Liver Transplantationmentioning

confidence: 99%