Thiamine and Cardiovascular Disease: A Literature Review

DiNicolantonio, James J.; Liu, Jing; O’Keefe, James H.

doi:10.1016/j.pcad.2018.01.009

Cited by 85 publications

(55 citation statements)

References 34 publications

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“…Direct measurement of serum thiamine is not a reliable indicator of total body thiamine stores as most of it is present inside the cells. The erythrocyte transketolase activity (ETKA) is an indirect measure of thiamine levels in the body and has high sensitivity as erythrocytes are the first cell line to be affected by low thiamine levels [4]. Another useful method is high-performance liquid chromatography (HPLC) to directly measure TPP concentration in erythrocytes.…”

Section: Introductionmentioning

confidence: 99%

Thiamine Therapy for Heart Failure: a Promise or Fiction?

Kattoor

Goel

Mehta

2018

Cardiovasc Drugs Ther

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Section: Introductionmentioning

confidence: 99%

Thiamine Therapy for Heart Failure: a Promise or Fiction?

Kattoor

Goel

Mehta

2018

Cardiovasc Drugs Ther

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“…Current prevention guidelines recommendations are a percentage of trans-unsaturated fatty acids <1% of energy intake, consumption of < 5 g salt/day, limitation of alcoholic drinks and discouragement of sweetened/carbonated drinks (7). Even if there are studies (pro and con) on the impact that certain nutrients and vitamins may have on cardiovascular pathology (selenium -(37-40), thiamine - (41,42), vitamin C - (43,44), magnesium -(4-47), zinc (48), monitoring of intake within rehabilitation programs is rarely performed. The study of food menus and their adaptation to patients' particularities would involve nutritional analysis from the perspective of the recipe and preparation technology, providing information related to the nutritional and energy value of the menus, salt content, fat, saturated fat, sugar and particularly nutrients, vitamins (much more rarely evaluated, as mentioned before).…”

Section: Preliminary Results Stage I -Based On the Data Provided By Umentioning

confidence: 99%

Collaborative platform development in nutrition as support for cardiovascular patients’ rehabilitation

Sitar‐Tăut

Sitar-Tăut

Mican

et al. 2019

BALNEO

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Introduction. Enrollment of patients with cardiovascular disease in rehabilitation programs may contribute to implementation of a healthy lifestyle, including by promotion of a diet adequate for each patient’s profile. In this context, the current study is aimed at creating a traffic light system model allowing to obtain the development, innovation and diversification of menus and to improve the nutritional programs for this category of patients. Material and method. Based on the data provided by USDA Food Composition Databases, the composition in terms of different nutritive principles was determined for each ingredient and for each final menu. Comparison of menus depending on each nutritive principle, as well as comparison between menus and nutrient requirements according to indications for patients attending cardiovascular rehabilitation programs was made. Results. The traffic light system was developed, using color codes, comparing daily nutrient requirements with preparations’ content. Conclusions. The major benefit of the traffic light system would reside in the fact that starting from classic menus, an intervention on these can be achieved, and healthier, more nutritionally balanced models can be created, according to healthy nutrition principles. These new menus will be calorically and nutritionally adapted for patients attending cardiovascular rehabilitation programs. Key words: nutrition, rehabilitation, traffic light system,

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“…Most of the signs present were indicative of nervousness. Name et al and DiNicolantonio et al [16,17] mentioned that, thiamine deficiency can cause to two very dissimilar disorders -a dry and wet beriberi. Dry beriberi involves neurological complications, whilst, wet beriberi has the involvement of cardiovascular complications which include, enlargement of the heart which might culminate to a heart failure, therefore the blood brain barrier is interrupted and cerebral hypoperfusion occurs resulting in manifestations of nervousness which was detected in the present study.…”

Section: Discussionmentioning

confidence: 99%

Polioencephalomalacia Caused by Thiamine Deficiency in Sheep of Basrah Province, Iraq.

Alsaad

2020

NIDOC-ASRT

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Thiamine is a water-soluble vitamin that is not stored in the body and needs to be replaced with daily diet. It has significant role to play in carbohydrate and energy metabolism, as the thiamine is converted to aneurine pyrophosohate carboxylate which is critical in carbohydrate build up or break down. It is also required for the functioning of the heart, muscles, and nervous system, since tissues such as the brain and the heart are particularly compromised in thiamine deficiency [3]. Although ruminal microorganisms will P OLIOENCEPHALOMALACIA caused by thiamine deficiency in sheep of Basrah province have been diagnosed. This current research was conducted on 44 local sheep breeds 1-3 years old and of both sexes reared in Basrah province. Ten clinically normal local sheep breeds were selected as a controls. Diseased sheep show various clinical manifestations, such as anorexia, head pressing and muscular tremors, opisthotonus and nystagmus, incoordination and ataxia, Furthermore, circling with lateral deviation of the head (41%), recumbency and inability to stand and some sheep exhibit blindness (18.1%). Moreover, significant increase in respiratory and heart rate of diseased animals in comparison with control animals , while rumen motility was decreased significantly in affected animals compared to control group. Considerable changes were detected in biochemical parameters of affected sheep in comparison with controls. The gross pathological features and histopathological examination of dying or slaughtered sheep show pale discoloration of the dorsal cerebral cortex, especially the occipital lobes, which might indicate a necrosis. However, gross lesions might also represent flattening of cerebral gyri, hemorrhages, necrosis to cavitations in the gray matter of the occipital and temporal regions. The histopathological examinations revealed gliosis as well to vacuolative changes of some neurons. The white matter of brain showed also gliosis with wallerian degeneration of some neuronal axons and severe vaculation of neuronal cell body and central chromatolysis of some neurons. thiamine estimated by simple spectrophotometric method. It is concluded that thiamine deficiency is an important disease which could affect domesticated animals and result in economic losses, Therefore, good care and good management will be the ideal way to control the disease.

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Thiamine and Cardiovascular Disease: A Literature Review

Cited by 85 publications

References 34 publications

Thiamine Therapy for Heart Failure: a Promise or Fiction?

Thiamine Therapy for Heart Failure: a Promise or Fiction?

Collaborative platform development in nutrition as support for cardiovascular patients’ rehabilitation

Polioencephalomalacia Caused by Thiamine Deficiency in Sheep of Basrah Province, Iraq.

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