Compared vulnerabilities to small cardiac motions between different cameras used for myocardial perfusion imaging

Salvadori, Julien; Petegnief, Yolande; Sabbah, Remi; Morel, Olivier; Boulahdour, Hatem; Karcher, Gilles; Marie, Pierre-Yves; Imbert, Laëtitia

doi:10.1007/s12350-017-1175-6

Cited by 4 publications

(4 citation statements)

References 23 publications

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“…To date, CZT-SPECT studies published on brain perfusion [ 18 , 20 ] or on dopamine receptors [ 32 ] are scarce and involve only very limited study populations. However, the superiority of CZT-based detectors over the NaI-scintillator systems utilized by current Anger cameras has already been clearly established, even in the clinical routine of SPECT investigations, although mostly for dedicated cardiac cameras [ 21 , 33 , 34 ]. In previous cardiac SPECT studies, dedicated cardiac CZT cameras were shown to provide significant enhancements in image quality and especially, in spatial resolution and image contrast [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360° CZT camera

et al. 2020

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Objective The aim of this study was to compare brain perfusion SPECT obtained from a 360° CZT and a conventional Anger camera. Methods The 360° CZT camera utilizing a brain configuration, with 12 detectors surrounding the head, was compared to a 2-head Anger camera for count sensitivity and image quality on 30-min SPECT recordings from a brain phantom and from 99mTc-HMPAO brain perfusion in 2 groups of 21 patients investigated with the CZT and Anger cameras, respectively. Image reconstruction was adjusted according to image contrast for each camera. Results The CZT camera provided more than 2-fold increase in count sensitivity, as compared with the Anger camera, as well as (1) lower sharpness indexes, giving evidence of higher spatial resolution, for both peripheral/central brain structures, with respective median values of 5.2%/3.7% versus 2.4%/1.9% for CZT and Anger camera respectively in patients (p < 0.01), and 8.0%/6.9% versus 6.2%/3.7% on phantom; and (2) higher gray/white matter contrast on peripheral/central structures, with respective ratio median values of 1.56/1.35 versus 1.11/1.20 for CZT and Anger camera respectively in patients (p < 0.05), and 2.57/2.17 versus 1.40/1.12 on phantom; and (3) no change in noise level. Image quality, scored visually by experienced physicians, was also significantly higher on CZT than on the Anger camera (+ 80%, p < 0.01), and all these results were unchanged on the CZT images obtained with only a 15 min recording time. Conclusion The 360° CZT camera provides brain perfusion images of much higher quality than a conventional Anger camera, even with high-speed recordings, thus demonstrating the potential for repositioning brain perfusion SPECT to the forefront of brain imaging.

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Section: Discussionmentioning

confidence: 99%

High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360° CZT camera

et al. 2020

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“…The SH is performed using 32 subsets and iterated 9 times. Inter-iteration filtering is applied by convolution with a smoothing kernel with a central value of (1 − ω ), where ω is 0.125 [ 17 , 18 ]. The only distinction between the two reconstruction protocols is the number of iterations.…”

Section: Methodsmentioning

confidence: 99%

The D-SPECT SH reconstruction protocol: improved quantification of small left ventricle volumes

Huang,

Zhang,

et al. 2024

EJNMMI Phys

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Background Due to spatial resolution limitations, conventional NaI-SPECT typically overestimates the left ventricular (LV) ejection fraction (EF) in patients with small LV volumes. The purpose of this study was to explore the clinical application value of the small heart (SH) reconstruction protocol embedded in the postprocessing procedure of D-SPECT. Methods We retrospectively analyzed patients who undergo both D-SPECT and echocardiography (Echo) within one week. Patients with small LV volume were defined as those with a rest end-systolic volume (rESV) ≤ 25 mL and underwent reconstruction using the standard (SD) reconstruction protocol. The SH protocol was deemed successful in correcting the LVEF value if it decreased by 5% or more compared to the SD protocol. The ROC curve was used to calculate the optimal cutoff value of the SH protocol. LVEF, ESV and EDV were computed with SD and SH, respectively. Echo was performed as a reference, and Echo-LVEF, ESV, and EDV were calculated using the Teichholz formula. One-way ANOVA was used to compare these parameters among the three groups. Results The final study included 209 patients (73.21% female, age 67.34 ± 7.85 years). Compared with the SD protocol, the SH protocol significantly decreased LVEF (67.43 ± 7.38% vs. 71.30 ± 7.61%, p < 0.001). The optimal cutoff value for using the SH protocol was rESV > 17 mL (AUC = 0.651, sensitivity = 78.43%, specificity = 45.57%, p = 0.001). In the subgroup of rESV > 17 mL, there was no significant difference in LVEF (61.84 ± 4.67% vs. 62.83 ± 2.85%, p = 0.481) between the SH protocol and Echo, and no significant difference was observed in rESV (26.92 ± 3.25 mL vs. 27.94 ± 7.96 mL, p = 0.60) between the SH protocol and Echo. Conclusion This pilot study demonstrated that the SH reconstruction protocol was able to effectively correct the overestimation of LVEF in patients with small LV volumes. Particularly, in the rESV > 17 mL subgroup, the time and computing power waste could be reduced while still ensuring the accuracy of the LVEF value and image quality.

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“…2,3 Originally, all SPECT systems consisted of one or more Anger detectors that rotated about the patient, so that abrupt patient motion in the caudal direction (corresponding to the ''z'' direction in the paper by Salvadori et al 4 ) produced image data at those projections that are inconsistent with the image counts acquired at other projections. Reconstruction algorithms that are provided with data that are inconsistent from one projection to another often produce artifactual regional decreases in apparent myocardial perfusion that are misinterpreted as genuine perfusion defects.…”

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confidence: 99%

“…4 Generally speaking, among the various types of potential imaging artifacts, those due to patient motion are particularly troubling because of the wide variability of their effects on scans. Whereas center-of-rotation calibration errors and single detector camera tilt errors produce highly predictable artifactual perfusion pattern problems, 10 the effects of patient motion are highly variable, since patients can move in numerous ways that include twisting, slumping, sliding, spasming, and coughing motions at different times and at different projection angles during the course of the acquisition.…”

mentioning

confidence: 99%

Rotating and stationary SPECT system patient motion myocardial perfusion artifacts

Nichols

Tosh

2019

Journal of Nuclear Cardiology

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Compared vulnerabilities to small cardiac motions between different cameras used for myocardial perfusion imaging

Cited by 4 publications

References 23 publications

High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360° CZT camera

High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360° CZT camera

The D-SPECT SH reconstruction protocol: improved quantification of small left ventricle volumes

Rotating and stationary SPECT system patient motion myocardial perfusion artifacts

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