Correction: Corrigendum: Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second

Abstract

In the version of this Article originally published, the x-axis units of Fig. 3a were incorrectly given as ms, and should have read µs. This has now been corrected. Two places in the text also needed amending to reflect this change: the penultimate sentence of Fig. 3c,d caption now starts 'Microsecond pulses are used' , and the penultimate sentence of the second paragraph of 'Device performance' has been changed to begin 'Device A was measured continuously over 230 days with microsecond write-read pulses' . All have now been corrected in the online versions of the Article.Corrigendum: Robust resistive memory devices using solution-processable metal-coordinated azo aromatics Sreetosh Goswami, Adam J. Matula, Santi P. Rath, Svante Hedström, Surajit Saha, Meenakshi Annamalai, Debabrata Sengupta, Abhijeet Patra, Siddhartha Ghosh, Hariom Jani, Soumya Sarkar, Mallikarjuna Rao Motapothula, Christian A. Nijhuis, Jens Martin, Sreebrata Goswami, Victor S. Batista and T. Venkatesan Nature Materials 16, 1216-1224 (2017); published online 23 October 2017; corrected after print 4 December 2017.In the version of this Article originally published, Fig. 6 was not cited; a citation to it has now been added at the end of the first paragraph of 'Discussion' . This has been corrected in all versions of the Article.Corrigendum: Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second © 2 0 1 7 M a c m i l l a n P u b l i s h e r s L i m i t e d , p a r t o f S p r i n g e r N a t u r e . A l l r i g h t s r e s e r v e d .

Cellular Mechanotransduction: From Tension to Function

“…Integrin affinity for its ECM ligand can be regulated within the cell in a process called “inside-out signaling” or prompted by extracellular mechanical stimuli, inducing a high-affinity conformation change ( Chen W. et al, 2012 ). Following such events, integrins are activated, cluster and reinforce molecular links at the cell-matrix interface ( Oria et al, 2017 ; Strohmeyer et al, 2018 ). Their extracellular domain contacts the ECM, while the cytoplasmic tail interacts with cytoskeletal actin through a number of docking proteins, forming the inner core of the FAs.…”

Building a microfluidic cell culture platform with stiffness control using Loctite 3525 glue

“…For instance, it has been shown that stiffness involves a different organization of the cytoskeleton and controls the extent of crosslinked actin filaments inside these cells 22 . Recently, some interesting works have focused on the time response of fibroblasts adhesions to dissipative substrate, showing the great importance of designing materials complying with the characteristic timescales that are responsible for cellular mechanoresponse 23,24 . Spreading in fibroblasts indeed seems to be determined not only by the elastic properties of substrates but also to their viscoelastic properties 25,26 .…”