Effectiveness of Intra-Articular Injections of Sodium Hyaluronate or Corticosteroids for Intracapsular Temporomandibular Disorders: A Systematic Review and Meta-Analysis

Moldez, Marlon A; Camones, Victor R; Ramos, Guillermo; Padilla, Mariela; Enciso, Reyes

doi:10.11607/ofph.1783

Cited by 28 publications

(27 citation statements)

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“…However, most of the studies associate them with more invasive procedures, such as arthrocentesis that is very effective in the TMJDs and can be performed on an outpatient basis under local anesthesia. These procedures also do not require elaborate and expensive equipment for their use [16,17,[21][22][23][24]28,29,33]. However, we were looking for a more conservative but equally effective approach to the same problems and these were pointed out during this research.…”

Section: Discussionmentioning

confidence: 93%

“…In the current literature, there are several studies that have compared the outcome of the use of hyaluronic acid and corticosteroids [16,[28][29][30][31][32], but very few have focused on the benefits of the use of platelet-rich plasma [33][34][35]. To the authors' knowledge, there is no research currently available that compares the use of these three products in TMJ arthralgia.…”

Section: Discussionmentioning

confidence: 99%

“…It should be noted that, as demonstrated in several previous studies, the use of bite splint shows a high efficacy [36], as well as the use of intra-articular infiltrations of betamethasone, hyaluronic acid and platelet-rich plasma [28,29,[31][32][33][34][35]37,38]. However, most of the studies associate them with more invasive procedures, such as arthrocentesis that is very effective in the TMJDs and can be performed on an outpatient basis under local anesthesia.…”

Section: Discussionmentioning

confidence: 99%

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Different Treatments in Patients with Temporomandibular Joint Disorders: A Comparative Randomized Study

Sousa

López-Valverde

et al. 2020

Medicina

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Background and Objectives: Temporomandibular joint disorders (TMJDs) are associated with pain and reduced jaw mobility. The aim of this study was to compare the outcome of patients with TMJ arthralgia when submitted to four different treatment modalities, in some cases using intra-articular injections of substances with anti-inflammatory properties and in others, a more conservative approach consisting only of a bite splint. Materials and Methods: The sample was made up of 80 patients, randomly distributed into 4 groups of 20 patients each. Each patient was given a nocturnal bite splint. One of the groups was treated with the bite splint only, while each patient in the other 3 was injected with betamethasone, sodium hyaluronate, or platelet-rich plasma in addition to using the bite splint. Two variables were assessed, namely pain intensity between 0 to 10 according to the visual analogue scale and maximum pain-free mouth opening in mm. The patients were evaluated at four different points: at the beginning of the treatment, as well as one week, one month and six months after initiation. Results: The results showed that maximum pain-free mouth opening improved in all the groups that made up the sample, with either a reduction in pain severity or with no pain. However, the group injected with platelet-rich plasma yielded the best results after six months, while patients treated with sodium hyaluronate or betamethasone obtained the best results at the end of the first week. Conclusions: We concluded that all the treatments used caused a reduction in pain and increased pain-free mouth opening. The splint combined with the platelet-rich plasma injection achieved long-term success.

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Different Treatments in Patients with Temporomandibular Joint Disorders: A Comparative Randomized Study

Sousa

López-Valverde

et al. 2020

Medicina

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“…The beneficial effects of viscosupplementation with HA in TMD have not been probed satisfactory and are not more effective that of corticosteroids and NSAIDs [35,55,56]. Also, although there was no significant difference between the effectiveness HA and corticoids intraarticular injections, there was some evidence that HA was better than placebo [57]. However, most studies report a decrease in pain levels independently by the TMD [58].…”

Section: Intraarticular Delivery Of Hyaluronic Acidmentioning

confidence: 99%

Nonsurgical Strategies for the Treatment of Temporomandibular Joint Disorders

Cabrera-Freitag¹,

Cobo²,

Muriel³

et al. 2019

Cartilage Tissue Engineering and Regeneration Techniques

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Temporomandibular disorders are common maxillofacial disturbs of different etiologies (traumatic, inflammatory, degenerative, or congenital) that course with pain and dysfunctions of the temporomandibular joint. The treatment of these disorders includes systematically administered drugs (especially nonsteroid antiinflammatory drugs and corticoids), physical therapies, and minimally invasive therapies that require intraarticular injections. These techniques are directed to clean or drain the articular cavity, to deliver intraarticularly drugs, biologically active compounds (as platelet-rich plasma), or to enhance lubrication (hyaluronic acid). Moreover, minimally invasive strategies are used in regenerative medicine for to deliver cells and stem cells, and nano-or micro-biomaterials. Surgery of temporomandibular disorders is only used in grave diseases that require arthrodesis or remotion of the temporomandibular joint. This review updates the nonsurgical therapeutic strategies to treat temporomandibular disorders, focusing the attention in the articular delivery or hyaluronic acid and platelet-rich plasma, two minimally invasive widely used at present.

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“…Moldez и соавт. [79] представили метаанализ 7 РКИ, посвященных сравнению ГлК с плацебо и ГК. Согласно полученным данным, по эффективности ГлК не отличалась от ГК у таких пациентов.…”

Section: рис 1 механизм действия экзогенной глкunclassified

Hyaluronic acid preparations in the treatment of osteoarthritis: is it clear to us?

Каратеев¹,

Погожева²,

Амирджанова³

et al. 2018

RJTAO

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Osteoarthritis (OA) is a progressive joint disease that causes persistent pain, limited joint function, disability, and loss of social activity. One of the most popular OA treatment options is intra-articular (I/A) hyaluronic acid (HA) injections. This procedure was introduced into clinical practice in the early 1980s and is used universally. To date, there is no consensus on the therapeutic value of HA. Many investigations confirm that HA is effective as not only a symptomatic agent, but also a structure-modifying one. Some works also show that the effect of HA is equal or only slightly superior to that of placebo (I/A saline injection). The review describes the mechanism of action and comparative efficacy of various (lowand high-molecular weight) HA preparations, as well as the safety of their use in real clinical practice.

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Effectiveness of Intra-Articular Injections of Sodium Hyaluronate or Corticosteroids for Intracapsular Temporomandibular Disorders: A Systematic Review and Meta-Analysis

Cited by 28 publications

References 0 publications

Different Treatments in Patients with Temporomandibular Joint Disorders: A Comparative Randomized Study

Different Treatments in Patients with Temporomandibular Joint Disorders: A Comparative Randomized Study

Nonsurgical Strategies for the Treatment of Temporomandibular Joint Disorders

Hyaluronic acid preparations in the treatment of osteoarthritis: is it clear to us?

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