Coiled-coil motif in LBD16 and LBD18 transcription factors are critical for dimerization and biological function in arabidopsis

Pandey, Shashank K.; Kim, Jungmook

doi:10.1080/15592324.2017.1411450

Cited by 10 publications

(3 citation statements)

References 21 publications

(40 reference statements)

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“…The homo-and heterodimerization of LBD proteins are thought to be an important determinant of LR formation [26,41]. The AtbZIP59 transcription factor has been reported to form complexes with LBDs to direct auxin-induced callus formation and LR development [42].…”

Section: The Product Of the Auxin-induced Gene Prh1 Controls Lr Formamentioning

confidence: 99%

PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana

et al. 2020

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The development of lateral roots in Arabidopsis thaliana is strongly dependent on signaling directed by the AUXIN RESPONSE FACTOR7 (ARF7), which in turn activates LATERAL ORGAN BOUNDARIES DOMAIN (LBD) transcription factors (LBD16, LBD18 and LBD29). Here, the product of PRH1, a PR-1 homolog annotated previously as encoding a pathogenresponsive protein, was identified as a target of ARF7-mediated auxin signaling and also as participating in the development of lateral roots. PRH1 was shown to be strongly induced by auxin treatment, and plants lacking a functional copy of PRH1 formed fewer lateral roots. The transcription of PRH1 was controlled by the binding of both ARF7 and LBDs to its promoter region.

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Section: The Product Of the Auxin-induced Gene Prh1 Controls Lr Formamentioning

confidence: 99%

PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana

et al. 2020

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“…The homo- and heterodimerization of LBD proteins are thought to be an important determinant of LR formation [29, 30]. The AtbZIP59 transcription factor has been reported to form complexes with LBDs to direct auxin-induced callus formation and LR development [31].…”

Section: Discussionmentioning

confidence: 99%

PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development inArabidopsis thaliana

Zhang

Tao

Sun

et al. 2019

Preprint

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18The development of lateral roots in Arabidopsis thaliana is strongly dependent on 19 signaling directed by the AUXIN RESPONSE FACTOR7 (ARF7), which in turn 20 activates LATERAL ORGAN BOUNDARIES DOMAIN (LBD) transcription factors 21 (LBD16, 18, 29 and 33). Here, the product of PRH1, a PR-1 homolog annotated 22 previously as encoding a pathogen-responsive protein, was identified as a target of 23 ARF7-mediated auxin signaling and also as participating in the development of lateral 24 roots. PRH1 was shown to be strongly induced by auxin treatment, and plants lacking 25 a functional copy of PRH1 formed fewer lateral roots. The transcription of PRH1 was 26 controlled by the binding of both ARF7 and LBDs to its promoter region. An 27 interaction was detected between PRH1 and GATA23, a protein which regulates cell 28 identity in lateral root founder cells. 29 2 30 31 Author Summary 32 In Arabidopsis thaliana AUXIN RESPONSE FACTOR7 (ARF7)-mediated auxin 33 signaling plays a key role in lateral roots (LRs) development. The LATERAL ORGAN 34 BOUNDARIES DOMAIN (LBD) transcription factors (LBD16, 18, 29 and 33) act 35 downstream of ARF7-mediated auxin signaling to control LRs formation. Here, the 36 PR-1 homolog PRH1 was identified as a novel target of both ARF7 and LBDs 37 (especially the LBD29) during auxin induced LRs formation, as both ARF7 and 38LBDs were able to bind to the PRH1 promoter. More interestingly, PRH1 has a 39 physical interaction with GATA23, which has been also reported to be up-regulated 40 by auxin and influences LR formation through its regulation of LR founder cell 41 identity. Whether the interaction between GATA23 and PRH1 affects the stability 42 and/or the activity of either (or both) of these proteins remains an issue to be explored. 43 This study provides improves new insights about how auxin regulates lateral root 44 development. 3 45 Introduction 46 The architecture of the root system depends on the density of lateral roots (LRs) 47 formed along with the extent of root branching. LRs are initiated from mature 48 pericycle cells lying adjacent to the xylem pole, referred to in Arabidopsis thaliana as 49 the xylem pole pericycle [1, 2]. A subset of these cells, namely the founder cells, 50 undergo a series of highly organized divisions to form an LR primordium, which 51 eventually develops into an LR. The entire process of LR development, from its 52 initiation to its emergence, is regulated by auxin [1, 3, 4]. The accumulation of auxin 53 in protoxylem cells results in the priming of neighboring pericycle cells to gain 54 founder cell identity, forming an LR pre-branch site [5, 6]. This auxin signaling is 55 mediated by the proteins ARF7 and ARF19, which act in the IAA28-dependent 56 pathway [7, 8]. LR initiation depends on the transcriptional activation, through the 57 involvement of the transcription factor LBD16 and LBD18, of either E2Fa or CDK 58 A1;1 and CYC B1;1 [9, 10]. Other downstream targets such as EXP14 and EXP17 and 59 the products of certain cell wall loosening-related genes ...

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“…These feedback loops may contribute to the continued LR growth in response to auxin in Arabidopsis [101]. The coiled-coil motifs in AtLBD16 and AtLBD18 transcription factors determine their DNA-binding properties, including DNA-binding diversity, specificity and affinity, which functions in the transcriptional regulation of different cellular processes and biological pathways in Arabidopsis [103]. By contrast, AtLBD14 was not responsive to auxin, but it was downregulated by ABA and participates in ABA-mediated regulation of LR formation [51,73] (Figure 2, Table 2).…”

Section: Functions Of Lbd Proteins In Class Ib Cladementioning

confidence: 99%

Phylogeny and Functions of LOB Domain Proteins in Plants

Zhang

et al. 2020

IJMS

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Lateral organ boundaries (LOB) domain (LBD) genes, a gene family encoding plant-specific transcription factors, play important roles in plant growth and development. At present, though there have been a number of genome-wide analyses on LBD gene families and functional studies on individual LBD proteins, the diverse functions of LBD family members still confuse researchers and an effective strategy is required to summarize their functional diversity. To further integrate and improve our understanding of the phylogenetic classification, functional characteristics and regulatory mechanisms of LBD proteins, we review and discuss the functional characteristics of LBD proteins according to their classifications under a phylogenetic framework. It is proved that this strategy is effective in the anatomy of diverse functions of LBD family members. Additionally, by phylogenetic analysis, one monocot-specific and one eudicot-specific subclade of LBD proteins were found and their biological significance in monocot and eudicot development were also discussed separately. The review will help us better understand the functional diversity of LBD proteins and facilitate further studies on this plant-specific transcription factor family.

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Coiled-coil motif in LBD16 and LBD18 transcription factors are critical for dimerization and biological function in arabidopsis

Cited by 10 publications

References 21 publications

PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana

PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana

PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development inArabidopsis thaliana

Phylogeny and Functions of LOB Domain Proteins in Plants

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