Impact of anti‐infective periodontal therapy on parameters of vascular health

Abstract

Efficacious resolution of periodontal inflammation may beneficially impact on vascular health.

Retrospectively analysed tooth loss in periodontally compromised patients: Long‐term results 10 years after active periodontal therapy—Patient‐related outcomes

“…How is TLP linked to cardiovascular disease? Considering the association of cardiovascular with periodontal disease, 61‐64 it may be that teeth with periodontal lesions are more likely to be extracted in cardiovascular diseased patients to lower the inflammatory load. On the other hand, drugs described due to cardiovascular disease (e.g.…”

Association between periodontal inflammation and hypertension using periodontal inflamed surface area and bleeding on probing

“…Periodontal inflamed surface area reflects the surface area of bleeding pocket epithelium in square millimetres and is calculated using conventional clinical parameters of periodontal health, namely BoP combined with either periodontal pocket depth (PPD), or clinical attachment loss (CAL) and gingival recession (Nesse et al, ). PISA was effectively associated with systemic markers of low‐grade inflammation, such as CRP, and with parameters of vascular health (Jockel‐Schneider et al, ; Susanto et al, ).…”

Does Periodontal Treatment Help in Arterial Hypertension Control? A Systematic Review of Literature

“…In 2017, Jockel-Schneider et al 20 performed a clinical intervention trial with 55 patients also comparing periodontal treatment (scaling and root planning) with or without administration of systemic antibiotic (amoxicillin 500 mg and metronidazole 400 mg thrice daily for 7 days). The periodontal parameters stated to be elected were: appearance of periodontal pockets ≥6 mm at a minimum of four teeth.…”

“…The population of the studies varied from 40 to 125 patients depending on the article. Moreover, the types of studies were different: five randomized clinical trials, [15][16][17][18][19] one interventional prospective cohort study, 10 one clinical intervention trial, 20 and one pilot intervention study. 21 There were also different types of periodontal treatment compared.…”

“…While some authors compared basic periodontal therapy (dental hygiene) and intensive periodontal treatment (scaling and root planning), 19 some others compared intensive periodontal treatment with or without administration of antibiotics, both local antimicrobials 15 and systemic. 16,20 There was another group of studies that had an intervention group where periodontal intensive treatment was performed and a control group that received no treatment until the end of the study. 17,18 Finally, there were two studies that only had one group of patients that received nonsurgical periodontal treatment, dental hygiene, or scaling and root planning according to need.…”