Preservation of motor maps with increased motor evoked potential amplitude threshold in RMT determination

Abstract

Our study demonstrates the feasibility of increasing the MEP detection threshold to 500 μV in rMT determination and motor area mapping with nTMS without losing precision.

TMS Motor Mapping Methodology and Reliability: A Structured Review

“…Yet, some efforts have been made to understand the effects of intensities on motor maps. One group found good correlation between maps produced at 105% of threshold using a 50 and 500 μV threshold for MEP amplitude, but not for a 300 μV amplitude ( Lucente et al, 2018 ). Overall this suggests that selection of a mapping intensity, when informed by stimulus-response curve characteristics, may reduce response variability compared to simply selecting intensity in relation to RMT.…”

Table_1.docx

“…Yet, some efforts have been made to understand the effects of intensities on motor maps. One group found good correlation between maps produced at 105% of threshold using a 50 and 500 µV threshold for MEP amplitude, but not for a 300 µV amplitude (Lucente et al, 2018). Overall this suggests that selection of a mapping intensity, when informed by stimulus-response curve characteristics, may reduce response variability compared to simply selecting intensity in relation to RMT.…”

Table_2.docx

“…Yet, some efforts have been made to understand the effects of intensities on motor maps. One group found good correlation between maps produced at 105% of threshold using a 50 and 500 µV threshold for MEP amplitude, but not for a 300 µV amplitude (Lucente et al, 2018). Overall this suggests that selection of a mapping intensity, when informed by stimulus-response curve characteristics, may reduce response variability compared to simply selecting intensity in relation to RMT.…”