Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in Chile

Musa, Gada; Henríquez, Fernando; Muñoz-Neira, Carlos; Delgado, Carolina; Lillo, Patricia; Slachevsky, Andrea

doi:10.1590/1980-57642016dn11-020005

Cited by 38 publications

(31 citation statements)

References 31 publications

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“…This tool has shown high internal consistency reliability for the frequency/severity product scores (a = 0.88) and for the specific severity (a = 0.87) and frequency (a = 0.88) ratings [24]. The brief version of this scale, the NPI-Q, was validated in Chile with excellent results [25]. The test-retest showed a significant correlation for total symptoms scale ( r = 0.89) and for distress scale ( r = 0.90).…”

Section: Methodsmentioning

confidence: 99%

Predictors of unmet needs in Chilean older people with dementia: a cross-sectional study

et al. 2019

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Background The needs of people with dementia (PWD) have not been assessed in any Latin American country. Several European countries have already related unmet needs with quality of life, caregiver’s age, burden, stress, anxiety and depression. The aim of this study was to identify met and unmet needs in Chilean older adults with dementia and to determine if those needs were associated with PWD’s, their informal caregivers’ and social factors. Method This was a cross-sectional study. One-hundred and sixty-six informal caregivers and their care recipients were interviewed. PWD was assessed about cognitive function and their caregivers answered instruments about PWD’s needs, functional status and behavioral and psychological symptoms. Caregiver’s burden, depression, anxiety and social support were also evaluated. A stepwise multiple linear regression analysis was performed to determine predictors of unmet needs in Chilean PWD. Results The most frequent met needs were “Looking after home” (81.3%%), “Food” (78.9%) and “Selfcare” (75.3%). Most common unmet needs were “Daily living activities” (39.2%), “Company” (36.1%), and “Memory” (34.9%). Caregivers’ lower age was correlated to a higher number of PWD’s unmet needs (r s = −.216; p < 0.005). Higher PWD’s dependence was associated with higher number of unmet needs (r s = .177; p < 0.05). The best predictors of unmet needs were caregivers’ low level of social support, high burden, young age and high level of anxiety. Conclusion It is necessary to address psychological and social needs of PWD. The fact that PWD’s unmet needs were associated mostly with caregivers’ factors, highlights the importance of considering both, the PWD and their informal caregivers as targets of institutional support. It is expected that recently launched national public policies decrease PWD’s unmet needs by the provision of new services for them and their informal caregivers.

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Section: Methodsmentioning

confidence: 99%

Predictors of unmet needs in Chilean older people with dementia: a cross-sectional study

et al. 2019

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“…The NPI has shown good reliability across translation into multiple languages including Chinese, [21][22][23][24] Chilean Spanish, 25 Korean, 26,27 Turkish, 28 Brazilian Portugese, 6,29 European Portugese, 30 Farsi, 31 Icelandic, 32 Japanese, [33][34][35] Norwegian, 36 Polish, 37 Greek, 38 Nigerian, 39 Danish, 40 Dutch, 41 Italian, 42 and European Spanish. 43,44 The validity of the NPI in non-Western cultures has rarely been rigorously examined and remains an area to be researched.…”

Section: Translations and International Applications Of The Npimentioning

confidence: 99%

The Neuropsychiatric Inventory: Development and Applications

Cummings

2020

J Geriatr Psychiatry Neurol

112

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Reasons for the Study: The Neuropsychiatric Inventory (NPI) has been used for studies of neuropsychiatric symptoms in neurodegenerative disorders for the past 25 years. This article reviews the history of the development and application of the NPI. Main Findings: The NPI consists of 10 (or 12) items that are assayed with questions, subquestions, and ratings of frequency and severity. The NPI has been shown to be valid and reliable. The NPI has been translated into approximately 40 languages; it has 4 of versions designed for different clinical applications. The NPI studies show contrasting profiles of behavioral symptoms in different neurologic disorders. The NPI has been used in approximately 350 clinical trials. In economic studies, the NPI captures the cost of behavioral symptoms in dementias. Principle Conclusions: The NPI is a useful instrument for capturing behavioral changes in Alzheimer disease and other neurodegenerative disorders.

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“…Several informant-based scales have been developed in order to assess neuropsychiatric symptoms. The Neuropsychiatric Inventory Questionnaire [105,106] aims to identify the presence of hallucinations, delusions, depression, apathy, and other signs that occur in both pathologies. The Cambridge Behavioral Inventory [107] is used to assess behavioral and cognitive changes along with daily life activities as well.…”

Section: Neuropsychiatric Featuresmentioning

confidence: 99%

Alzheimer’s Disease or Behavioral Variant Frontotemporal Dementia? Review of Key Points Toward an Accurate Clinical and Neuropsychological Diagnosis

Musa

Slachevsky

Muñoz-Neira

et al. 2020

JAD

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Alzheimer's disease (AD) and frontotemporal dementia (FTD) are the most common neurodegenerative early-onset dementias. Despite the fact that both conditions have a very distinctive clinical pattern, they present with an overlap in their cognitive and behavioral features that may lead to misdiagnosis or delay in diagnosis. The current review intends to summarize briefly the main differences at the clinical, neuropsychological, and behavioral levels, in an attempt to suggest which aspects would facilitate an adequate diagnosis in a clinical setting, especially in Latin American and low-and middle-income countries, where the resources needed for a differential diagnosis (such as MRI or biomarkers) are not always available. A timely diagnosis of AD and FTD have significant implications for the medical management and quality of life of patients and careers.

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Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in Chile

Cited by 38 publications

References 31 publications

Predictors of unmet needs in Chilean older people with dementia: a cross-sectional study

Predictors of unmet needs in Chilean older people with dementia: a cross-sectional study

The Neuropsychiatric Inventory: Development and Applications

Alzheimer’s Disease or Behavioral Variant Frontotemporal Dementia? Review of Key Points Toward an Accurate Clinical and Neuropsychological Diagnosis

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