We evaluated the applicability of the neck and sternal notch (Sn) as anatomical landmarks for paediatric chest compression (cc) depth using chest computed tomography. the external anteroposterior diameter (eApD) of the neck and chest at the Sn level, mid-point between two landmarks (midlandmark), and eApD of the chest at the lower half of the sternum (eDLH) were measured. to estimate the depths of the landmarks from a virtual point at the same height as the position for cc, we calculated the differences between the EAPDs of the neck, SN, mid-landmark, and EDLH. We analysed the relationship between the depths of the landmarks and one-third eDLH using Bland-Altman plots. In all, 506 paediatric patients aged 1-9 years were enrolled. The depths of the neck, SN, and midlandmark were 53.7 ± 10.0, 37.8 ± 8.5, and 45.8 ± 9.0 mm, respectively. The mean one-third EDLH was 46.8 ± 7.0 mm. The means of the differences between the depths of the neck and one-third EDLH, depths of the SN and one-third EDLH, and depths of the mid-landmark and one-third EDLH were 9.0, −6.9, and 1.0 mm, respectively. The SN and neck are inappropriate landmarks to guide compression depth in paediatric cpR. Current cardiopulmonary resuscitation (CPR) guidelines emphasise the importance of chest compressions (CCs). CCs are important not only for adults but also for infants and children, who have relatively high rates of respiratory arrest 1. The American Heart Association (AHA) and European Resuscitation Council (ERC) recommends a CC depth of at least one-third of the chest anteroposterior (AP) dimension in children 1,2. Given the characteristics of children whose body sizes vary greatly with age, different CC depths may be required for them during CPR. Because of this variability, it may be difficult to meet the recommended criterion for fractional CC depths in actual child CPR situations. In line with these concerns, a previous study observed that the target CC depth recommended by the guidelines was not achieved in 81% of CPR events 3. Identifying an anatomical landmark close to one-third of the child's chest dimension may increase the probability of achieving the target CC depth during CPR. However, studies on anatomical landmarks of CC depth are limited. In a recent study using chest computed tomography (CT) in adults, Kim et al. reported that the suprasternal notch could be an anatomical landmark corresponding to one-fourth of the AP diameter of the chest 4. However, in that study, one-fourth was less than one-third fractional CC depth recommended for children. Additionally, the thorax grows and develops from birth to adolescence. The ratio of the vertical diameter to the transverse diameter of the chest varies from approximately 1:1 in infants to approximately 1:1.5 in adults 5. Considering the difference in the aspect ratio between adults and children, the landmark for CC depth in children is likely to be deeper than the sternal notch, which is the landmark identified in adults. In this context, we present the neck as a landmark for CC depth f...