291 Procalcitonin for Detection of Serious Bacterial Infections in Children Presenting With Fever Without Source: A Systematic Review and Meta-analysis

Yo, Chia‐Hung; Hsieh, Pei‐Chen; Lee, C.; Lee, S.; Chang, Shi-Chuan; Tsai, Kun-Tong; Chen, S.

doi:10.1016/j.annemergmed.2011.06.321

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“…Clinical symptoms of bacterial infection are nonspecifi c and the confi rmation of the diagnosis is often diffi cult. When PCT is compared to other markers of infection/infl ammation, it seems to be more sensitive and more specifi c for monitoring bacterial infections in humans [12,13]. For these reasons, the aim of the present study was to evaluate the levels of PCT, CRP and WBC in monitoring postoperative complications in dogs following ovariohysterectomy.…”

Section: Introductionmentioning

confidence: 99%

Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy

Gürbüz

Ulutaş

2017

Acta Veterinaria

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CRP and WBC are the most widely used markers of infl ammation in veterinary clinical diagnosis. Also, PCT is a specifi c APP marker of bacterial diseases in humans. This study evaluated the levels of PCT, CRP and WBC during postoperative monitoring of bitches undergoing ovariohysterectomy. Thirteen adult clinically healthy female crossbreed dogs aged between 7-24 months were used in the study. Ovariohysterectomy was performed via medial laparotomy using routine procedures. Blood samples were collected from the cephalic vein at 1, 4 and 7 days after surgery (post-op period). Mean serum concentration of PCT, CRP and WBC levels were increased after the surgery. CRP concentrations and WBC counts were increased signifi cantly (p<0.001) on the fi rst day after the operation and decreased to basal values. However, the PCT rise was not signifi cant. CRP and WBC levels increased rapidly and decreased to normal values in dogs with ovariohysterectomy. CRP and WBC may be of help to determine the possible postoperative complications. Besides, aseptic surgical trauma did not affect PCT levels in dogs. Future studies are needed on canine PCT response focusing on specifi c bacterial infections.

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Section: Introductionmentioning

confidence: 99%